Di(Hydroxyethyl)Ether

Di(Hydroxyethyl)Ether

SCHEMBL145454

C=CCOC.OCCOCCO

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.48
MAPK1 P28482 1/20 0.48
MEN1 O00255 3/20 0.46
KMT2A Q03164 3/20 0.46
ALDH1A1 P00352 1/20 0.40
THRB P10828 1/20 0.37
HTT P42858 1/20 0.37
MAPT P10636 1/20 0.37
POLB P06746 1/20 0.34
TDP1 Q9NUW8 1/20 0.32
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
CA7 P43166 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9719267 0.98 MEN1 (0.50) TSHRMAPK1MEN1KMT2AALDH1A1
SCHEMBL7649866 0.98 MEN1 (0.50) TSHRMAPK1MEN1KMT2AALDH1A1
SCHEMBL28438414 0.98 MEN1 (0.50) TSHRMAPK1MEN1KMT2AALDH1A1
Pentaethylene Glycol SCHEMBL7695796 0.98 MEN1 (0.50) TSHRMAPK1MEN1KMT2AALDH1A1
Hexaethylene Glycol SCHEMBL9719216 0.98 MEN1 (0.50) TSHRMAPK1MEN1KMT2AALDH1A1
Triethylene Glycol SCHEMBL148187 0.98 MEN1 (0.50) TSHRMAPK1MEN1KMT2AALDH1A1
Ethylene Glycol SCHEMBL1803897 0.85
SCHEMBL1618032 0.85 MEN1 (0.46) TSHRMAPK1MEN1KMT2AALDH1A1
2-Methoxyethanol SCHEMBL10630116 0.84 MEN1 (0.42) TSHRMAPK1MEN1KMT2AALDH1A1
Ethylene Glycol SCHEMBL7695790 0.82 TSHR (0.35) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4624479-A1 HYDROSILANE COMPOSITION AND METHOD FOR PREPARING HYDROSILYLATION PRODUCT SHIN-ETSU CHEMICAL CO., LTD. (JP) 2025-10-01 EP disclosed
US-12296325-B2 Catalyst for hydrosilylation reaction, hydrogenation reaction, and hydrosilane reduction reaction KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2025-05-13 US disclosed
WO-2024111422-A1 HYDROGEN SILANE COMPOSITION AND METHOD OR PRODUCING HYDROSILYLATION REACTANT 信越化学工業株式会社 2024-05-30 WO disclosed
CN-117304474-A Polyether silicone oil material, preparation method and application thereof, and medicine 中国矿业大学 2023-12-29 CN disclosed
US-20230241594-A1 CATALYST FOR HYDROSILYLATION REACTION, HYDROGENATION REACTION, AND HYDROSILANE REDUCTION REACTION KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2023-08-03 US disclosed
EP-3590596-B1 CATALYST FOR HYDROSILYLATION REACTION, HYDROGENATION REACTION, AND HYDROSILANE REDUCTION REACTION UNIV KYUSHU NAT UNIV CORP (JP) 2023-07-12 EP disclosed
EP-3689891-B1 COBALT COMPLEX, PRODUCTION METHOD THEREFOR, AND CATALYST FOR HYDROSILYLATION REACTION UNIV KYUSHU NAT UNIV CORP (JP) 2023-03-01 EP disclosed
US-20220401938-A1 CATALYST FOR HYDROSILYLATION REACTION, HYDROGENATION REACTION, AND HYDROSILANE REDUCTION REACTION KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2022-12-22 US disclosed
CN-110366449-B Catalyst for hydrosilylation, hydrogenation, and hydrosilane reduction 国立大学法人九州大学 2022-10-21 CN disclosed
CN-115135307-A Carrier for cell delivery 株式会社ITO 2022-09-30 CN disclosed
EP-1159332-A1 POLYSILOXANE POLYMERS WITH MULTIPLE OLIGOOXYETHYLENE SIDE CHAINS WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2001-12-05 EP disclosed
WO-2000053661-A1 POLYSILOXANE POLYMERS WITH MULTIPLE OLIGOOXYETHYLENE SIDE CHAINS WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2000-09-14 WO disclosed
US-6077910-A POLYMERIZABLE MACROMOLECULE HAVING AN ANIONIC GROUP OR A POLYMERIZABLE MACROMOLECULE WHICH CAN GENERATE THE ANIONIC GROUP. DAICEL-HUELS LTD. (JP) 2000-06-20 US disclosed
EP-0823409-A1 Cement retarder and cement retardative sheet Daicel-Huels Ltd. (JP) 1998-02-11 EP disclosed
EP-0030807-B1 SHAPED BIOMEDICAL ARTICLES MADE OF POLYSILOXANE POLYMERS BAUSCH & LOMB INCORPORATED (US) 1985-06-19 EP disclosed
EP-0035080-B1 SHAPED BIOMEDICAL ARTICLES FORMED FROM POLYSILOXANE POLYMERS BAUSCH & LOMB INCORPORATED (US) 1984-08-15 EP disclosed
EP-0035080-A1 Shaped biomedical articles formed from polysiloxane polymers BAUSCH & LOMB INCORPORATED (US) 1981-09-09 EP disclosed
EP-0030807-A1 Shaped biomedical articles made of polysiloxane polymers BAUSCH & LOMB INCORPORATED (US) 1981-06-24 EP disclosed
US-4260725-A Hydrophilic contact lens made from polysiloxanes which are thermally bonded to polymerizable groups and which contain hydrophilic sidechains BAUSCH & LOMB INCORPORATED (US) 1981-04-07 US disclosed
US-4259467-A Hydrophilic contact lens made from polysiloxanes containing hydrophilic sidechains BAUSCH & LOMB INCORPORATED (US) 1981-03-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12296325-B2 Catalyst for hydrosilylation reaction, hydrogenation reaction, and hydrosilane reduction reaction H1-0, HVCN1, H1-2 TSHR 2660/4885MAPK1 1974/4885MEN1 441/4885
US-20230241594-A1 CATALYST FOR HYDROSILYLATION REACTION, HYDROGENATION REACTION, AND HYDROSILANE REDUCTION REACTION H1-0, HVCN1, H1-2 TSHR 2660/4885MAPK1 1974/4885MEN1 441/4885
US-20220401938-A1 CATALYST FOR HYDROSILYLATION REACTION, HYDROGENATION REACTION, AND HYDROSILANE REDUCTION REACTION H1-0, HVCN1, H1-2 TSHR 2664/4885MAPK1 1967/4885MEN1 439/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.