Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 7/20 | 0.73 |
| ▸ | CNR2 | P34972 | 2/20 | 0.73 |
| ▸ | CKS1B | P61024 | 3/20 | 0.52 |
| ▸ | SKP1 | P63208 | 3/20 | 0.52 |
| ▸ | SKP2 | Q13309 | 3/20 | 0.52 |
| ▸ | PTPN11 | Q06124 | 4/20 | 0.45 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | SMO | Q99835 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14545352 | 0.90 | CNR1 (0.75) | CNR1CNR2CKS1BSKP1SKP2 | |
| SCHEMBL14545609 | 0.90 | CNR1 (0.69) | CNR1CNR2CKS1BSKP1SKP2 | |
| SCHEMBL14545036 | 0.89 | CNR1 (0.58) | CNR1CNR2CKS1BSKP1SKP2 | |
| SCHEMBL14545679 | 0.89 | CNR1 (0.57) | CNR1CNR2CKS1BSKP1SKP2 | |
| SCHEMBL4694605 | 0.89 | CNR1 (0.58) | CNR1CNR2CKS1BSKP1SKP2 | |
| SCHEMBL14545355 | 0.88 | CNR1 (0.72) | CNR1CNR2CKS1BSKP1SKP2 | |
| SCHEMBL14545093 | 0.87 | CNR1 (0.71) | CNR1CNR2CKS1BSKP1SKP2 | |
| SCHEMBL14545081 | 0.86 | CNR1 (0.77) | CNR1CNR2CKS1BSKP1SKP2 | |
| SCHEMBL14545670 | 0.86 | CNR1 (0.75) | CNR1CNR2CKS1BSKP1SKP2 | |
| SCHEMBL14545751 | 0.85 | CNR1 (0.71) | CNR1CNR2CKS1BSKP1SKP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070078135-A1 | Substituted heteroaryl CB1 antagonists | NEUROGEN CORPORATION (US) | 2007-04-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070078135-A1 | Substituted heteroaryl CB1 antagonists | CNR1, CNR2, OPRL1 | CNR1 1/4885CNR2 2/4885CKS1B 1836/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.