Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 8/20 | 0.57 |
| ▸ | CNR2 | P34972 | 2/20 | 0.57 |
| ▸ | CKS1B | P61024 | 2/20 | 0.55 |
| ▸ | SKP1 | P63208 | 2/20 | 0.55 |
| ▸ | SKP2 | Q13309 | 2/20 | 0.55 |
| ▸ | PTPN11 | Q06124 | 5/20 | 0.47 |
| ▸ | PIM1 | P11309 | 2/20 | 0.38 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.38 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HTR3B | O95264 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | HTR3A | P46098 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14545642 | 0.94 | CNR1 (0.59) | CNR1CNR2CKS1BSKP1SKP2 | |
| SCHEMBL14545673 | 0.89 | CNR1 (0.73) | CNR1CNR2CKS1BSKP1SKP2 | |
| SCHEMBL14544967 | 0.87 | CNR1 (0.58) | CNR1CNR2CKS1BSKP1SKP2 | |
| SCHEMBL14545464 | 0.87 | CNR1 (0.47) | CNR1CNR2CKS1BSKP1SKP2 | |
| SCHEMBL14545718 | 0.85 | CNR1 (0.63) | CNR1CNR2CKS1BSKP1SKP2 | |
| SCHEMBL14545057 | 0.85 | CNR1 (0.60) | CNR1CNR2CKS1BSKP1SKP2 | |
| SCHEMBL14545098 | 0.85 | CNR1 (0.58) | CNR1CNR2CKS1BSKP1SKP2 | |
| SCHEMBL14545038 | 0.84 | CNR1 (0.53) | CNR1CNR2CKS1BSKP1SKP2 | |
| SCHEMBL14544985 | 0.84 | CNR1 (0.58) | CNR1CNR2CKS1BSKP1SKP2 | |
| SCHEMBL14545048 | 0.84 | CNR1 (0.58) | CNR1CNR2CKS1BSKP1SKP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070078135-A1 | Substituted heteroaryl CB1 antagonists | NEUROGEN CORPORATION (US) | 2007-04-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070078135-A1 | Substituted heteroaryl CB1 antagonists | CNR1, CNR2, OPRL1 | CNR1 1/4885CNR2 2/4885CKS1B 1836/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.