Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14582600 | 0.84 | GSK3B (0.39) | KDM4EALDH1A1MAPTRAB9A | |
| SCHEMBL13288471 | 0.80 | KDM4E (0.47) | KDM4EALDH1A1MAPTRAB9A | |
| SCHEMBL14528821 | 0.80 | CSNK2B (0.36) | KDM4EALDH1A1MAPTRAB9A | |
| SCHEMBL12953369 | 0.77 | KDM4E (0.49) | KDM4EALDH1A1MAPTRAB9A | |
| SCHEMBL26871183 | 0.77 | KDM4E (0.36) | KDM4EALDH1A1MAPTRAB9AGRM2 | |
| SCHEMBL13911663 | 0.76 | — | — | |
| SCHEMBL26871001 | 0.75 | KDM4E (0.35) | KDM4EALDH1A1MAPTRAB9A | |
| SCHEMBL13650606 | 0.75 | ALDH1A1 (0.44) | KDM4EALDH1A1MAPTRAB9A | |
| SCHEMBL19455177 | 0.75 | MAPT (0.59) | KDM4EALDH1A1MAPTRAB9A | |
| SCHEMBL26871180 | 0.74 | KCNH2 (0.36) | KDM4EALDH1A1MAPTRAB9AGRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007044449-A2 | NOVEL PYRAZOLOPYRIMIDINES AS CYCLIN DEPENDENT KINASE INHIBITORS | SCHERING CORPORATION (US) | 2007-04-19 | — | — | WO | disclosed |