Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 5/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | GLA | P06280 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL425266 | 0.80 | CNR2 (0.37) | CNR2SMN1; SMN2KDM4EALDH1A1GAA | |
| SCHEMBL18478526 | 0.78 | SMN1; SMN2 (0.43) | CNR2CYP3A4SMN1; SMN2ALDH1A1GAA | |
| SCHEMBL13612712 | 0.77 | ALDH1A1 (0.38) | CNR2SMN1; SMN2KDM4EALDH1A1GAA | |
| SCHEMBL12608295 | 0.74 | CNR2 (0.34) | CNR2SMN1; SMN2KDM4EALDH1A1GAA | |
| SCHEMBL16727329 | 0.72 | CNR2 (0.34) | CNR2SMN1; SMN2KDM4EALDH1A1GAA | |
| SCHEMBL16885247 | 0.72 | CNR2 (0.39) | CNR2SMN1; SMN2KDM4EALDH1A1GAA | |
| SCHEMBL2834119 | 0.72 | CNR2 (0.34) | CNR2SMN1; SMN2KDM4EALDH1A1GAA | |
| SCHEMBL14195168 | 0.71 | CNR2 (0.33) | CNR2CNR1 | |
| SCHEMBL4114260 | 0.70 | CNR2 (0.31) | CNR2 | |
| SCHEMBL4114263 | 0.70 | DPP4 (0.36) | CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007038669-A2 | DIARYLAMINE-CONTAINING COMPOUNDS AND COMPOSITIONS, AND THEIR USE AS MODULATORS OF C-KIT RECEPTORS | IRM LLC (BM) | 2007-04-05 | — | — | WO | disclosed |