Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 9/20 | 0.72 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.65 |
| ▸ | PKM | P14618 | 2/20 | 0.56 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.54 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.54 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.54 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.54 |
| ▸ | PLG | P00747 | 1/20 | 0.54 |
| ▸ | F2 | P00734 | 1/20 | 0.52 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.51 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4732514 | 1.00 | FOLH1 (0.72) | FOLH1TDP1PKMPRSS1PRSS2 | |
| SCHEMBL6973486 | 0.96 | FOLH1 (0.67) | FOLH1TDP1PKMPRSS1PRSS2 | |
| SCHEMBL1405877 | 0.88 | FOLH1 (0.56) | FOLH1TDP1PKMPRSS1PRSS2 | |
| SCHEMBL10044328 | 0.88 | TDP1 (0.72) | FOLH1TDP1PKMPRSS1PRSS2 | |
| SCHEMBL29928558 | 0.87 | TDP1 (0.75) | FOLH1TDP1PKMCAPN1 | |
| SCHEMBL9807479 | 0.87 | TDP1 (0.77) | FOLH1TDP1PKMCAPN1 | |
| SCHEMBL6972386 | 0.87 | FOLH1 (0.57) | FOLH1TDP1PKMPRSS1PRSS2 | |
| SCHEMBL12809772 | 0.87 | FOLH1 (0.57) | FOLH1TDP1PKMPRSS1PRSS2 | |
| SCHEMBL13497854 | 0.86 | PRSS1 (0.67) | FOLH1TDP1PKMPRSS1PRSS2 | |
| SCHEMBL13497916 | 0.86 | PRSS1 (0.67) | FOLH1TDP1PKMPRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007042469-A2 | ANTICOAGULANT ANTITHROMBOTIC DUAL INHIBITORS COMPRISING A BIOTIN LABEL | N.V. ORGANON (NL) | 2007-04-19 | — | — | WO | disclosed |