Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 9/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.47 |
| ▸ | PKM | P14618 | 3/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.45 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.45 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.45 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.45 |
| ▸ | PLG | P00747 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ABL1 | P00519 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | IDE | P14735 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | F2 | P00734 | 1/20 | 0.45 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6972386 | 1.00 | FOLH1 (0.57) | FOLH1TDP1PKMPRSS1PRSS2 | |
| SCHEMBL13485722 | 0.89 | FOLH1 (0.54) | FOLH1TDP1PKMPRSS1PRSS2 | |
| SCHEMBL4732514 | 0.87 | FOLH1 (0.72) | FOLH1TDP1PKMPRSS1PRSS2 | |
| SCHEMBL14547441 | 0.87 | FOLH1 (0.72) | FOLH1TDP1PKMPRSS1PRSS2 | |
| SCHEMBL1405877 | 0.86 | FOLH1 (0.56) | FOLH1TDP1PKMPRSS1PRSS2 | |
| SCHEMBL6973486 | 0.85 | FOLH1 (0.67) | FOLH1TDP1PKMPRSS1PRSS2 | |
| SCHEMBL21361154 | 0.83 | TDP1 (0.50) | FOLH1TDP1PKMPRSS1PRSS2 | |
| SCHEMBL739034 | 0.79 | TDP1 (0.63) | FOLH1TDP1PKMPRSS1PRSS2 | |
| SCHEMBL29512013 | 0.79 | TDP1 (0.63) | FOLH1TDP1PKMPRSS1PRSS2 | |
| SCHEMBL21361155 | 0.79 | TDP1 (0.49) | FOLH1TDP1PKMPRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1991271-B1 | ANTICOAGULANT ANTITHROMBOTIC DUAL INHIBITORS COMPRISING A BIOTIN LABEL | ORGANON NV (NL) | 2011-03-09 | — | — | EP | disclosed |
| WO-2007042469-A2 | ANTICOAGULANT ANTITHROMBOTIC DUAL INHIBITORS COMPRISING A BIOTIN LABEL | N.V. ORGANON (NL) | 2007-04-19 | — | — | WO | disclosed |