Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14548684 | 0.89 | KIF11 (0.63) | KIF11KCNH2 | |
| SCHEMBL14537509 | 0.89 | KIF11 (0.78) | KIF11 | |
| SCHEMBL14548760 | 0.87 | KIF11 (1.00) | KIF11 | |
| SCHEMBL14432808 | 0.87 | KIF11 (1.00) | KIF11 | |
| SCHEMBL14548685 | 0.87 | KIF11 (0.76) | KIF11 | |
| SCHEMBL14537459 | 0.87 | KIF11 (1.00) | KIF11 | |
| SCHEMBL14537457 | 0.87 | KIF11 (1.00) | KIF11 | |
| SCHEMBL1255723 | 0.81 | KIF11 (0.67) | KIF11 | |
| SCHEMBL14548682 | 0.81 | KIF11 (0.73) | KIF11 | |
| SCHEMBL3905388 | 0.81 | KIF11 (0.70) | KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8765817-B1 | Selective inhibitors of EG5 motors and methods of use | ARROWHEAD CENTER, INC. (US) | 2014-07-01 | — | — | US | disclosed |
| US-8349899-B1 | Selective inhibitors of EG5 motors and methods of use | ARROWHEAD CENTER, INC. (US) | 2013-01-08 | — | — | US | disclosed |