Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 12/20 | 0.55 |
| ▸ | CHRM2 | P08172 | 8/20 | 0.55 |
| ▸ | CHRM4 | P08173 | 8/20 | 0.55 |
| ▸ | NAMPT | P43490 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 2/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4870913 | 0.86 | CHRM1 (0.53) | CHRM1CHRM2CHRM4NAMPTSMN1; SMN2 | |
| SCHEMBL4868985 | 0.86 | CHRM1 (0.53) | CHRM1CHRM2CHRM4NAMPTSMN1; SMN2 | |
| SCHEMBL4868987 | 0.86 | CHRM1 (0.53) | CHRM1CHRM2CHRM4NAMPTSMN1; SMN2 | |
| SCHEMBL4873762 | 0.82 | CHRM1 (0.50) | CHRM1CHRM2CHRM4NAMPTSMN1; SMN2 | |
| SCHEMBL4867618 | 0.82 | CHRM1 (0.50) | CHRM1CHRM2CHRM4NAMPTSMN1; SMN2 | |
| SCHEMBL4867624 | 0.82 | CHRM1 (0.50) | CHRM1CHRM2CHRM4NAMPTSMN1; SMN2 | |
| SCHEMBL8740549 | 0.76 | NAMPT (0.65) | NAMPTMEN1KMT2AMMP9MMP2 | |
| SCHEMBL3461884 | 0.76 | NAMPT (0.65) | NAMPTMEN1KMT2AMMP9MMP2 | |
| SCHEMBL8092135 | 0.76 | NAMPT (0.65) | NAMPTMEN1KMT2AMMP9MMP2 | |
| SCHEMBL3106753 | 0.76 | NAMPT (0.58) | CHRM1CHRM2CHRM4NAMPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1608617-B1 | MUSCARINIC AGONISTS | LILLY CO ELI (US) | 2013-01-09 | — | — | EP | disclosed |