Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT1 | Q96EB6 | 3/20 | 0.81 |
| ▸ | HEXA | P06865 | 6/20 | 0.71 |
| ▸ | HEXB | P07686 | 6/20 | 0.71 |
| ▸ | OGA | O60502 | 1/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.60 |
| ▸ | AHR | P35869 | 1/20 | 0.60 |
| ▸ | RAD52 | P43351 | 1/20 | 0.60 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.57 |
| ▸ | LTA4H | P09960 | 1/20 | 0.57 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.57 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.57 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bnipdpta SCHEMBL13909966 | 0.92 | SIRT1 (0.88) | SIRT1HEXAHEXBOGAKMT2A | |
| SCHEMBL13909979 | 0.92 | SIRT1 (0.88) | SIRT1HEXAHEXBOGAKMT2A | |
| SCHEMBL13909963 | 0.92 | SIRT1 (0.94) | SIRT1HEXAHEXBOGAKMT2A | |
| Bnipdeta SCHEMBL13909965 | 0.92 | SIRT1 (0.88) | SIRT1HEXAHEXBOGAKMT2A | |
| Bnipdadec SCHEMBL13909967 | 0.91 | SIRT1 (0.97) | SIRT1HEXAHEXBOGAKMT2A | |
| SCHEMBL13909960 | 0.91 | SIRT1 (0.97) | SIRT1HEXAHEXBOGAKMT2A | |
| SCHEMBL13909961 | 0.91 | SIRT1 (0.97) | SIRT1HEXAHEXBOGAKMT2A | |
| Bnipspd SCHEMBL13909975 | 0.91 | SIRT1 (0.91) | SIRT1HEXAHEXBOGAKMT2A | |
| Bnipdanon SCHEMBL13909969 | 0.91 | SIRT1 (0.97) | SIRT1HEXAHEXBOGAKMT2A | |
| SCHEMBL13909968 | 0.91 | SIRT1 (0.97) | SIRT1HEXAHEXBOGAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8350036-B2 | Bisnaphthalimidopropyl derivative compounds with anti-parasite and anti-cancer activity | UNIVERSIDADE DO PORTO (PT) | 2013-01-08 | — | — | US | disclosed |