Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 7/20 | 0.53 |
| ▸ | STS | P08842 | 1/20 | 0.50 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CSF1R | P07333 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14548949 | 0.94 | CYP19A1 (0.50) | CYP19A1STS | |
| SCHEMBL2060144 | 0.87 | CYP19A1 (0.68) | CYP19A1STS | |
| SCHEMBL13292511 | 0.83 | CYP19A1 (0.68) | CYP19A1STS | |
| SCHEMBL14549030 | 0.81 | CYP19A1 (0.52) | CYP19A1STSALDH1A1RAB9A | |
| SCHEMBL14548948 | 0.80 | CYP19A1 (0.74) | CYP19A1STSCYP1A2CYP3A4 | |
| SCHEMBL3240031 | 0.80 | CYP19A1 (0.64) | CYP19A1STS | |
| SCHEMBL2062891 | 0.74 | SMPD1 (0.56) | CYP19A1KDM4ECYP1A2CYP3A4CYP2D6 | |
| SCHEMBL14549043 | 0.74 | CYP19A1 (0.71) | CYP19A1STS | |
| SCHEMBL3235207 | 0.73 | CYP19A1 (0.67) | CYP19A1STS | |
| SCHEMBL3229611 | 0.73 | CYP19A1 (0.67) | CYP19A1STS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1446388-B1 | 1,2,4-TRIAZOLE DERIVATIVES CONTAINING A SULPHAMATE GROUP AS AROMATASE INHIBITORS | STERIX LTD (GB) | 2013-01-09 | — | — | EP | disclosed |