Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 18/20 | 0.74 |
| ▸ | STS | P08842 | 3/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2060137 | 0.85 | CYP19A1 (1.00) | CYP19A1STS | |
| SCHEMBL14548901 | 0.80 | CYP19A1 (0.53) | CYP19A1STSCYP1A2CYP3A4 | |
| SCHEMBL14549046 | 0.79 | CYP19A1 (0.72) | CYP19A1STS | |
| SCHEMBL13292451 | 0.78 | CYP19A1 (1.00) | CYP19A1STS | |
| SCHEMBL14549043 | 0.76 | CYP19A1 (0.71) | CYP19A1STS | |
| SCHEMBL13932224 | 0.75 | CYP19A1 (0.78) | CYP19A1STS | |
| SCHEMBL14548949 | 0.74 | CYP19A1 (0.50) | CYP19A1STS | |
| SCHEMBL8443366 | 0.72 | CYP19A1 (0.68) | CYP19A1STS | |
| SCHEMBL14548902 | 0.72 | CYP19A1 (0.52) | CYP19A1STS | |
| SCHEMBL2060244 | 0.72 | CYP19A1 (0.77) | CYP19A1STS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1446388-B1 | 1,2,4-TRIAZOLE DERIVATIVES CONTAINING A SULPHAMATE GROUP AS AROMATASE INHIBITORS | STERIX LTD (GB) | 2013-01-09 | — | — | EP | disclosed |