Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.50 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | RAD52 | P43351 | 1/20 | 0.43 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12608632 | 0.87 | MAPT (0.63) | MAPTMEN1KMT2ALMNAPOLB | |
| SCHEMBL12608626 | 0.82 | MAPT (0.56) | MAPTMEN1KMT2ALMNAPOLB | |
| SCHEMBL30013273 | 0.82 | MAPT (0.66) | MAPTMEN1KMT2ALMNAPOLB | |
| SCHEMBL12608625 | 0.82 | MAPT (0.56) | MAPTMEN1KMT2ALMNAPOLB | |
| SCHEMBL15495623 | 0.82 | MAPT (0.57) | MAPTMEN1KMT2ALMNAPOLB | |
| SCHEMBL11833660 | 0.81 | MAPT (0.70) | MAPTMEN1KMT2ALMNAPOLB | |
| SCHEMBL11825503 | 0.80 | MAPT (0.55) | MAPTMEN1KMT2ALMNAPOLB | |
| SCHEMBL148001 | 0.79 | MAPT (0.85) | MAPTMEN1KMT2ALMNAPOLB | |
| SCHEMBL29539965 | 0.79 | MAPT (0.85) | MAPTMEN1KMT2ALMNAPOLB | |
| SCHEMBL3039635 | 0.77 | MAPT (0.59) | MAPTMEN1KMT2ALMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2356093-B1 | Carbazole compounds and therapeutic uses of the compounds | INCURON LLC (RU) | 2013-01-09 | — | — | EP | disclosed |