Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.55 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11828899 | 0.93 | MAPT (0.49) | MAPTRXFP1HTTPOLBATM | |
| SCHEMBL11833660 | 0.86 | MAPT (0.70) | MAPTRXFP1HTTPOLBATM | |
| SCHEMBL12608625 | 0.84 | MAPT (0.56) | MAPTRXFP1HTTPOLBATM | |
| SCHEMBL6608471 | 0.81 | MAPT (0.62) | MAPTRXFP1HTTPOLBATM | |
| SCHEMBL14548911 | 0.80 | MAPT (0.57) | MAPTRXFP1HTTPOLBATM | |
| SCHEMBL12608632 | 0.79 | MAPT (0.63) | MAPTRXFP1HTTPOLBATM | |
| SCHEMBL11830811 | 0.79 | MAPT (0.67) | MAPTRXFP1HTTPOLBATM | |
| SCHEMBL12608697 | 0.79 | MAPT (0.50) | MAPTRXFP1HTTPOLBATM | |
| SCHEMBL11822106 | 0.78 | MAPT (0.50) | MAPTRXFP1HTT | |
| SCHEMBL11832005 | 0.77 | KDM4E (0.44) | MAPTHTTMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3988208-A | FOR GLUCOSE | BOEHRINGER MANNHEIM G.M.B.H. (DT) | 1976-10-26 | — | — | US | disclosed |
| US-3975398-A | INDICATOR FOR DETERMINATION OF GLUCOSE | BOEHRINGER MANNHEIM G.M.B.H. (DT) | 1976-08-17 | — | — | US | disclosed |