SCHEMBL1455006

SCHEMBL1455006

Cc1ccc(Nc2ccccc2)c2ccccc12

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 5/20 0.65
MEN1 O00255 3/20 0.65
KMT2A Q03164 3/20 0.65
TDP1 Q9NUW8 3/20 0.65
KDM4E B2RXH2 2/20 0.65
MAPT P10636 2/20 0.65
GLA P06280 1/20 0.65
RECQL P46063 1/20 0.65
CYP1A2 P05177 3/20 0.54
ALDH1A1 P00352 5/20 0.53
CDC25B P30305 4/20 0.53
HPGD P15428 3/20 0.53
HSD17B10 Q99714 3/20 0.53
ALOX15 P16050 3/20 0.53
ATM Q13315 2/20 0.53
TSHR P16473 2/20 0.53
TP53 P04637 1/20 0.53
CYP3A4 P08684 1/20 0.53
POLB P06746 1/20 0.49
SMN1; SMN2 Q16637 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL6142229 0.98 GAA (0.63) GAAMEN1KMT2ATDP1KDM4E
Hydrochloric Acid SCHEMBL27676841 0.98 GAA (0.63) GAAMEN1KMT2ATDP1KDM4E
SCHEMBL1921282 0.94 CYP1A2 (0.56) GAAMEN1KMT2ATDP1KDM4E
SCHEMBL22251521 0.90 GAA (0.76) GAAMEN1KMT2ATDP1KDM4E
SCHEMBL1920772 0.88 GAA (0.50) GAAMEN1KMT2ATDP1KDM4E
SCHEMBL12190480 0.88 HPGD (0.52) GAAMEN1KMT2ATDP1KDM4E
SCHEMBL19849964 0.87 CYP1A2 (0.65) GAAMEN1KMT2ATDP1KDM4E
SCHEMBL11962221 0.87 GAA (0.85) GAAMEN1KMT2ATDP1KDM4E
SCHEMBL17696884 0.84 GAA (0.47) GAAMEN1KMT2ATDP1KDM4E
SCHEMBL22251525 0.83 KMT2A (0.50) GAAMEN1KMT2ATDP1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9821074-B2 Pyrrolobenzodiazepines and conjugates thereof GENENTECH, INC. (US) 2017-11-21 US disclosed
CN-101001600-B Multicomponent kit and method for dyeing keratin fibers WELLA AG 2013-01-02 CN disclosed
US-7914966-B2 Modified polymers and their use in the production of lithographic printing plate precursors EASTMAN KODAK COMPANY (US) 2011-03-29 US disclosed
US-7910687-B2 Conjugated polymers containing arylamine units, the representation thereof and the use of the same MERCK PATENT GMBH (DE) 2011-03-22 US disclosed
CN-1984778-B Method for making negative-working heat-sensitive lithographic printing plate precursor AGFA GEVAERT 2010-12-29 CN disclosed
CN-100549060-C Contain the unitary conjugated polymers of arylamine and preparation and purposes MERCK PATENT GMBH (DE) 2009-10-14 CN disclosed
US-20070269727-A1 Modified Polymers and Their Use in the Production of Lithographic Printing Plate Precursors KODAK POLYCHROME GRAPHICS GMBH (DE) 2007-11-22 US disclosed
CN-101065163-A Colouring agents containing cationic indazoline-thiazolazo dyes PROCTER & GAMBLE (US) 2007-10-31 CN disclosed
CN-101001921-A Cationic pyrazolone dyes method for production thereof and colouring agents for keratin fibres containing said compounds WELLA AG (DE) 2007-07-18 CN disclosed
EP-1803034-A2 HOLOGRAPHIC STORAGE MEDIUM General Electric Company (US) 2007-07-04 EP disclosed
EP-1765592-A1 METHOD FOR MAKING NEGATIVE-WORKING HEAT-SENSITIVE LITHOGRAPHIC PRINTING PLATE PRECURSOR Agfa Graphics N.V. (BE) 2007-03-28 EP disclosed
EP-1558662-B1 CONJUGATED POLYMERS CONTAINING ARYLAMINE UNITS, THE REPRESENTATION THEREOF AND THE USE OF THE SAME MERCK PATENT GMBH (DE) 2006-12-13 EP disclosed
WO-2006044243-A2 HOLOGRAPHIC STORAGE MEDIUM GENERAL ELECTRIC COMPANY A CORPORATION OF THE STATE OF NEW YORK (US) 2006-04-27 WO disclosed
US-20060058494-A1 Conjugated polymers containing arylamine units, the representation thereof and the use of the same CONVION ORGANIC SEMICONDUCTORS GMBH INTELLECTUAL PROPERTY GROUP (DE) 2006-03-16 US disclosed
WO-2006005688-A1 METHOD FOR MAKING NEGATIVE-WORKING HEAT-SENSITIVE LITHOGRAPHIC PRINTING PLATE PRECURSOR. AGFA-GEVAERT (BE) 2006-01-19 WO disclosed
CN-1232509-C Diaminopyrazole derivatives and dyes containing these compounds P & G KRYROER CO (US) 2005-12-21 CN disclosed
CN-1708528-A Conjugated polymers containing arylamine units, the preparation thereof and the use of the same COVION ORGANIC SEMICONDUCTORS (DE) 2005-12-14 CN disclosed
EP-1558662-A2 CONJUGATED POLYMERS CONTAINING ARYLAMINE UNITS, THE REPRESENTATION THEREOF AND THE USE OF THE SAME Covion Organic Semiconductors GmbH (DE) 2005-08-03 EP disclosed
WO-2004037887-A2 CONJUGATED POLYMERS CONTAINING ARYLAMINE UNITS, THE REPRESENTATION THEREOF AND THE USE OF THE SAME COVION ORGANIC SEMICONDUCTORS GMBH (DE) 2004-05-06 WO disclosed
CN-1441786-A Novel diamino pyrazole derivatives and dyes containing said compounds WELLA AG (DE) 2003-09-10 CN disclosed