SCHEMBL1920772

SCHEMBL1920772

Cc1ccc(Nc2ccc(-c3ccc(Nc4ccc(C)c5ccccc45)cc3)cc2)c2ccccc12

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 4/20 0.50
MEN1 O00255 3/20 0.50
KMT2A Q03164 3/20 0.50
CYP1A2 P05177 2/20 0.50
MAPT P10636 2/20 0.50
TDP1 Q9NUW8 2/20 0.50
KDM4E B2RXH2 1/20 0.50
GLA P06280 1/20 0.50
RECQL P46063 1/20 0.50
HPGD P15428 3/20 0.41
ALDH1A1 P00352 2/20 0.41
ATM Q13315 2/20 0.41
TP53 P04637 1/20 0.41
CYP3A4 P08684 1/20 0.41
ALOX15 P16050 1/20 0.41
TSHR P16473 1/20 0.41
CDC25B P30305 1/20 0.41
HSD17B10 Q99714 1/20 0.41
RAB9A P51151 2/20 0.41
PTGER4 P35408 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1921282 0.94 CYP1A2 (0.56) GAAMEN1KMT2ACYP1A2MAPT
SCHEMBL12190480 0.89 HPGD (0.52) GAAMEN1KMT2ACYP1A2MAPT
SCHEMBL1455006 0.88 GAA (0.65) GAAMEN1KMT2ACYP1A2MAPT
Hydrochloric Acid SCHEMBL27676841 0.86 GAA (0.63) GAAMEN1KMT2ACYP1A2MAPT
Hydrochloric Acid SCHEMBL6142229 0.86 GAA (0.63) GAAMEN1KMT2ACYP1A2MAPT
SCHEMBL19849964 0.83 CYP1A2 (0.65) GAAMEN1KMT2ACYP1A2MAPT
SCHEMBL1921284 0.79 CYP1A2 (0.59) GAAMEN1KMT2ACYP1A2MAPT
SCHEMBL12393968 0.79 ALDH1A1 (0.50) GAAMEN1KMT2ACYP1A2MAPT
SCHEMBL22251521 0.78 GAA (0.76) GAAMEN1KMT2ACYP1A2MAPT
SCHEMBL13979445 0.78 HPGD (0.48) GAAMEN1KMT2AMAPTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1528074-B1 NOVEL TRIARYLAMINE POLYMER, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF TOSOH CORP (JP) 2014-03-26 EP disclosed
EP-2327739-A1 Novel triarylamine polymer, process for its production and its use TOSOH CORPORATION (JP) 2011-06-01 EP disclosed
US-7608680-B2 Triarylamine polymer, process for producing the same, and use thereof TOSOH CORPORATION (JP) 2009-10-27 US disclosed
US-20060241278-A1 Novel triarylamine polymer, process for producing the same, and use thereof TOSOH CORPORATION (JP) 2006-10-26 US disclosed
US-20060017040-A9 Novel triarylamine polymer, process for producing the same, and use thereof SUZUKI TAKAO 2006-01-26 US disclosed
EP-1528074-A1 NOVEL TRIARYLAMINE POLYMER, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF Tosoh Corporation (JP) 2005-05-04 EP disclosed
US-20040262574-A1 Novel triarylamine polymer, process for producing the same, and use thereof TOSOH CORPORATION (JP) 2004-12-30 US disclosed