Sugi Predict

Sugi Predict / Compounds / SCHEMBL14550392

SCHEMBL14550392

SCHEMBL14550392

CC(=O)N[C@H]1CSSC[C@@H](C(=O)N2CCC[C@H]2C(=O)N2CCC[C@H]2C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCCCNC(=O)COCCOCCNC(=O)CCCCCCCCCCCCCCC(=O)O)C(N)=O)NC(=O)CNC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](Cc2c[nH]cn2)NC(=O)[C@H](CCC(=O)O)NC1=O

nearest known ligand 0.54

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ TSLP Q969D9 2/20 0.54
▸ IL23R Q5VWK5 15/20 0.52
▸ SSTR1 P30872 1/20 0.51
▸ SSTR2 P30874 1/20 0.51
▸ SSTR4 P31391 1/20 0.51
▸ SSTR3 P32745 1/20 0.51
▸ SSTR5 P35346 1/20 0.51
▸ F11 P03951 1/20 0.50
▸ GLP1R P43220 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16340653 0.92 IL23R (0.53) TSLPIL23RF11GLP1R
SCHEMBL14550284 0.91 IL23R (0.51) TSLPIL23RSSTR1SSTR2SSTR4
SCHEMBL14550452 0.91 SSTR1 (0.49) TSLPIL23RSSTR1SSTR2SSTR4
SCHEMBL29482514 0.90 TSLP (0.58) TSLPF11GLP1R
SCHEMBL14550455 0.88 MDM2 (0.48) TSLPIL23RSSTR1SSTR2SSTR4
SCHEMBL29392338 0.88 TSLP (0.57) TSLPIL23RF11GLP1R
SCHEMBL14552773 0.87 MDM2 (0.54) TSLPIL23RGLP1R
SCHEMBL14550441 0.87 MDM2 (0.58) IL23RGLP1R
SCHEMBL29476611 0.86 TSLP (0.54) TSLPIL23RF11
SCHEMBL16340625 0.86 IL23R (0.51) TSLPIL23R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130012432-A1 Peptides for Treatment of Obesity NOVO NORDISK A/S (DK) 2013-01-10 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130012432-A1 Peptides for Treatment of Obesity MC4R, GIPR, MC3R TSLP 177/4885IL23R 698/4885SSTR1 38/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.