SCHEMBL14550486

SCHEMBL14550486

CN[C@@H](CO)C(=O)N[C@@H](CCCCNC(=O)COCCOCCNC(=O)CCCCCCCCCCCCCCCC(=O)O)C(N)=O

nearest known ligand 0.55

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ GLP1R P43220 8/20 0.55
▸ TLR2 O60603 1/20 0.45
▸ SIRT5 Q9NXA8 2/20 0.43
▸ CCKAR P32238 6/20 0.41
▸ CCKBR P32239 6/20 0.41
▸ NMT2 O60551 1/20 0.40
▸ NMT1 P30419 1/20 0.40
▸ ROCK2 O75116 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14550408 0.99 GLP1R (0.54) GLP1RTLR2SIRT5CCKARCCKBR
SCHEMBL14550557 0.96 GLP1R (0.56) GLP1RTLR2SIRT5CCKARCCKBR
SCHEMBL14550228 0.96 GLP1R (0.56) GLP1RTLR2SIRT5CCKARCCKBR
SCHEMBL14550487 0.95 GLP1R (0.56) GLP1RTLR2SIRT5CCKARCCKBR
SCHEMBL14550380 0.93 GLP1R (0.58) GLP1RTLR2SIRT5CCKARCCKBR
SCHEMBL14550148 0.93 GLP1R (0.53) GLP1RTLR2CCKARCCKBRNMT2
SCHEMBL14550121 0.92 GLP1R (0.53) GLP1RTLR2CCKARCCKBRNMT2
SCHEMBL14550509 0.91 GLP1R (0.56) GLP1RSIRT5CCKARCCKBR
SCHEMBL13577551 0.91 GLP1R (0.56) GLP1RSIRT5CCKARCCKBR
SCHEMBL14550361 0.91 GLP1R (0.56) GLP1RSIRT5CCKARCCKBR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130012432-A1 Peptides for Treatment of Obesity NOVO NORDISK A/S (DK) 2013-01-10 — — US disclosed
US-20130012432-A1 Peptides for Treatment of Obesity NOVO NORDISK A/S (DK) 2013-01-10 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130012432-A1 Peptides for Treatment of Obesity MC4R, GIPR, MC3R GLP1R 5/4885TLR2 1212/4885SIRT5 1964/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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