SCHEMBL14550361

SCHEMBL14550361

CN[C@@H](CCCCNC(=O)COCCOCCNC(=O)CCCCCCCCCCCCCCCCC(=O)O)C(N)=O

nearest known ligand 0.56

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ GLP1R P43220 8/20 0.56
▸ EPHX2 P34913 3/20 0.39
▸ CCKAR P32238 4/20 0.39
▸ CCKBR P32239 4/20 0.39
▸ FOLH1 Q04609 2/20 0.39
▸ SIRT5 Q9NXA8 1/20 0.39
▸ ITGB3 P05106 1/20 0.39
▸ ITGA2B P08514 1/20 0.39
▸ EPOR P19235 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14550509 1.00 GLP1R (0.56) GLP1REPHX2CCKARCCKBRFOLH1
SCHEMBL14550390 1.00 GLP1R (0.56) GLP1REPHX2CCKARCCKBRFOLH1
SCHEMBL13577551 1.00 GLP1R (0.56) GLP1REPHX2CCKARCCKBRFOLH1
SCHEMBL13577532 0.92 GLP1R (0.69) GLP1RCCKARCCKBRFOLH1
SCHEMBL8115663 0.92 GLP1R (0.51) GLP1RCCKARCCKBRFOLH1SIRT5
SCHEMBL14550380 0.92 GLP1R (0.58) GLP1RCCKARCCKBRFOLH1SIRT5
SCHEMBL14819894 0.92 GLP1R (0.68) GLP1RCCKARCCKBR
SCHEMBL26059894 0.91 GLP1R (0.56) GLP1REPHX2FOLH1EPOR
SCHEMBL14550486 0.91 GLP1R (0.55) GLP1RCCKARCCKBRSIRT5
SCHEMBL18117506 0.91 GLP1R (0.63) GLP1REPHX2FOLH1EPOR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130012432-A1 Peptides for Treatment of Obesity NOVO NORDISK A/S (DK) 2013-01-10 — — US disclosed
US-20130012432-A1 Peptides for Treatment of Obesity NOVO NORDISK A/S (DK) 2013-01-10 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130012432-A1 Peptides for Treatment of Obesity MC4R, GIPR, MC3R GLP1R 5/4885EPHX2 4159/4885CCKAR 40/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback