Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 13/20 | 0.69 |
| ▸ | HTR2C | P28335 | 13/20 | 0.69 |
| ▸ | HTR2B | P41595 | 12/20 | 0.69 |
| ▸ | PNMT | P11086 | 1/20 | 0.50 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.50 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | DRD1 | P21728 | 3/20 | 0.42 |
| ▸ | DRD2 | P14416 | 2/20 | 0.42 |
| ▸ | DRD5 | P21918 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15779152 | 0.83 | HTR2A (0.46) | HTR2AHTR2CHTR2BPNMTASIC3 | |
| SCHEMBL1095595 | 0.81 | HTR2C (1.00) | HTR2AHTR2CHTR2BPNMTADRB1 | |
| SCHEMBL1095893 | 0.81 | HTR2C (1.00) | HTR2AHTR2CHTR2BPNMTADRB1 | |
| SCHEMBL1095465 | 0.81 | HTR2C (1.00) | HTR2AHTR2CHTR2BPNMTADRB1 | |
| SCHEMBL1097095 | 0.80 | HTR2A (0.69) | HTR2AHTR2CHTR2BPNMTADRB1 | |
| SCHEMBL1095854 | 0.80 | HTR2A (0.69) | HTR2AHTR2CHTR2BPNMTADRB1 | |
| SCHEMBL1095853 | 0.80 | HTR2A (0.69) | HTR2AHTR2CHTR2BPNMTADRB1 | |
| SCHEMBL22482807 | 0.80 | HTR2A (0.69) | HTR2AHTR2CHTR2BPNMTASIC3 | |
| Hydrochloric Acid SCHEMBL22469583 | 0.79 | HTR2A (0.67) | HTR2AHTR2CHTR2BPNMTASIC3 | |
| Hydrochloric Acid SCHEMBL22469889 | 0.79 | HTR2A (0.67) | HTR2AHTR2CHTR2BPNMTASIC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130012498-A1 | 5HT2C RECEPTOR MODULATORS | ARENA PHARMACEUTICALS, INC. | 2013-01-10 | — | — | US | disclosed |
| US-20130012498-A1 | 5HT2C RECEPTOR MODULATORS | ARENA PHARMACEUTICALS, INC. | 2013-01-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130012498-A1 | 5HT2C RECEPTOR MODULATORS | HTR2C, HTR2A, HTR1A | HTR2A 2/4885HTR2C 1/4885HTR2B 7/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.