D-Aspartate

D-Aspartate

SCHEMBL145539

N[C@H](CC(=O)O)C(=O)O

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

SLC6A2SLC6A3SSTR1SSTR2SSTR3SSTR5

The experimentally established mechanism targets of D-Aspartate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Aspartic Acid SCHEMBL31070222 1.00
Aspartic Acid SCHEMBL31673497 1.00
Aspartic Acid SCHEMBL11065189 1.00 GRIK1 (0.56)
Aspartic Acid SCHEMBL1526976 1.00 GRIK1 (0.56)
Aspartic Acid SCHEMBL3230 1.00
D-Aspartate SCHEMBL31235712 1.00 GRIK1 (0.56)
Aspartic Acid SCHEMBL11065185 1.00 GRIK1 (0.56)
Aspartic Acid SCHEMBL3231 1.00
Aspartic Acid SCHEMBL996424 1.00 GRIK1 (0.56)
Aspartic Acid SCHEMBL31673507 1.00

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 11115 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4746912-A1 ORGANIC CYTOTOXIN OLIGOMERS AND USES THEREOF AS A PAYLOAD IN ANTIBODY-DRUG CONJUGATES Simris Biologics GmbH (DE) 2026-05-27 EP claimed
CN-122074077-A Radiolabeled melanocortin 1 receptor-specific alpha-melanocyte stimulating hormone analogs for imaging or therapy 省卫生服务机构 2026-05-22 CN claimed
US-12630520-B2 Left-handed bicyclic morpholine and salt thereof, preparation method therefor, pharmaceutical composition, and use INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF MEDICAL SCIENCES (CN) 2026-05-19 US claimed
CN-122056386-A Moisture absorption resistant slow release microcapsule powder and preparation method and application thereof 大连医诺生物股份有限公司 2026-05-19 CN claimed
CN-122070294-A Stable vitreous material based on histidine, arginine and glutamic acid amino acids 阵序补丁有限公司 2026-05-19 CN claimed
CN-122030612-A Shear-resistant slow-release microcapsule powder and preparation method and application thereof 大连医诺生物股份有限公司 2026-05-15 CN claimed
US-20260131015-A1 NEODEGRADER CONJUGATES ORUM THERAPEUTICS INC (KR) 2026-05-14 US claimed
CN-122010885-A Oraglycone intermediate, preparation method thereof and method for preparing key intermediate of Oraglycone 江西同和药业股份有限公司 2026-05-12 CN claimed
US-20260124312-A1 BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR EPHA2 BICYCLETX LIMITED (GB) 2026-05-07 US claimed
US-20260125442-A1 PROCESS FOR PREPARING A GIP/GLP1 DUAL AGONIST LILLY CO ELI (US) 2026-05-07 US claimed
US-4127520-A ANALGESIC VETERANS ADMINISTRATION, THE UNITED STATES OF AMERICA AS REPRESENTED BY 1978-11-28 US claimed
US-4127519-A ANALGESIC VETERANS ADMINISTRATION, THE UNITED STATES OF AMERICA AS REPRESENTED BY 1978-11-28 US claimed
US-4127518-A ANALGESIC VETERANS ADMINISTRATION, THE UNITED STATES OF AMERICA AS REPRESENTED BY 1978-11-28 US claimed
US-4127522-A ANALGESIC VETERANS ADMINISTRATION, THE UNITED STATES OF AMERICA AS REPRESENTED BY 1978-11-28 US claimed
US-4127521-A ANALGESIC VETERANS ADMINISTRATION, THE UNITED STATES OF AMERICA AS REPRESENTED BY 1978-11-28 US claimed
US-4127517-A ANALGESIC VETERANS ADMINISTRATION, THE UNITED STATES OF AMERICA AS REPRESENTED BY 1978-11-28 US claimed
US-4127535-A ANALGESIC VETERANS ADMINISTRATION, THE UNITED STATES OF AMERICA AS REPRESENTED BY 1978-11-28 US claimed
US-4127537-A ANALGESIC VETERANS ADMINISTRATION, THE UNITED STATES OF AMERICA AS REPRESENTED BY 1978-11-28 US claimed
US-4127536-A ANALGESIC VETERANS ADMINISTRATION, THE UNITED STATES OF AMERICA AS REPRESENTED BY 1978-11-28 US claimed
US-4127530-A ANALGESIC VETERANS ADMINISTRATION, THE UNITED STATES OF AMERICA AS REPRESENTED BY 1978-11-28 US claimed