Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Aspartic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Aspartic Acid SCHEMBL31070222 | 1.00 | — | — | |
| D-Aspartate SCHEMBL145539 | 1.00 | — | — | |
| Aspartic Acid SCHEMBL31673497 | 1.00 | — | — | |
| Aspartic Acid SCHEMBL11065189 | 1.00 | GRIK1 (0.56) | — | |
| Aspartic Acid SCHEMBL1526976 | 1.00 | GRIK1 (0.56) | — | |
| Aspartic Acid SCHEMBL3230 | 1.00 | — | — | |
| D-Aspartate SCHEMBL31235712 | 1.00 | GRIK1 (0.56) | — | |
| Aspartic Acid SCHEMBL11065185 | 1.00 | GRIK1 (0.56) | — | |
| Aspartic Acid SCHEMBL996424 | 1.00 | GRIK1 (0.56) | — | |
| Aspartic Acid SCHEMBL31673507 | 1.00 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 811177 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6410494-B1 | — | — | None | — | — | US | claimed |
| US-9974833-B2 | Methods of using compositions comprising variants and fusions of FGF19 polypeptides for modulating bile acid homeostasis in a subject having pregnancy intrahepatic cholestasis | NGM BIOPHARMACEUTICALS, INC. (US) | 2018-05-22 | — | — | US | claimed |
| US-9978609-B2 | Low dishing copper chemical mechanical planarization | VERSUM MATERIALS US, LLC (US) | 2018-05-22 | — | — | US | claimed |
| US-9975915-B1 | Crystalline forms of nicotinoyl ribosides, modified derivatives thereof, and phosphorylated analogs thereof, and methods of preparation thereof | THE QUEEN'S UNIVERSITY OF BELFAST (GB) | 2018-05-22 | — | — | US | claimed |
| US-9976126-B2 | Modified glycine oxidase | AJINOMOTO CO., INC. (JP) | 2018-05-22 | — | — | US | claimed |
| US-9976184-B2 | Mutations in pancreatic neoplasms | THE JOHNS HOPKINS UNIVERSITY (US) | 2018-05-22 | — | — | US | claimed |
| US-9974851-B2 | Human rotavirus vaccine strains and diagnostics | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2018-05-22 | — | — | US | claimed |
| US-9976074-B2 | Self-suspending proppant particulates using canola protein-based hydrogel | HALLIBURTON ENERGY SERVICES, INC. (US) | 2018-05-22 | — | — | US | claimed |
| US-20180134742-A1 | CRYSTALLINE FORMS OF NICOTINOYL RIBOSIDES, MODIFIED DERIVATIVES THEREOF, AND PHOSPHORYLATED ANALOGS THEREOF, AND METHODS OF PREPARATION THEREOF | THE QUEEN'S UNIVERSITY OF BELFAST (GB) | 2018-05-17 | — | — | US | claimed |
| US-20180135085-A1 | AMINO ACID PRODUCTION | EVONIK DEGUSSA GMBH (DE) | 2018-05-17 | — | — | US | claimed |
| US-3963578-A | ASPARTATE, ETHYLENEDIAMINETETRAACETIC ACID, AMMONIUM SULFATE, SODIUM PHOSPHATE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1976-06-15 | — | — | US | claimed |
| US-3963613-A | Blood purification means | TANABE SEIYAKU CO., LTD. (JA) | 1976-06-15 | — | — | US | claimed |
| US-3962468-A | Spray-dried L-aspartic acid derivatives | GENERAL FOODS CORPORATION (US) | 1976-06-08 | — | — | US | claimed |
| US-3958581-A | Cosmetic composition containing a cationic polymer and divalent metal salt for strengthening the hair | L'OREAL (FR) | 1976-05-25 | — | — | US | claimed |
| US-3953294-A | STORAGE STABLE REAGENT CONTAINING NONIONIC SURFACTANT | MALLINCKRODT, INC. (US) | 1976-04-27 | — | — | US | claimed |
| US-3950513-A | NONTOXIC AMINO ACID | NOVO TERAPEUTISK LABORATORIUM A/S (DK) | 1976-04-13 | — | — | US | claimed |
| US-3943038-A | Method for producing amino acids by culturing hydrogen-oxidizing bacteria | AJINOMOTO CO., INC. (JA) | 1976-03-09 | — | — | US | claimed |
| US-3933783-A | Formation of peptide bonds in the presence of isonitriles | AJINOMOTO CO., INC. (JA) | 1976-01-20 | — | — | US | claimed |
| US-3933586-A | USING A PSEUDOMONACEA MICROORGANISM | LES PRODUITS ORGANIQUES DU SANTERRE ORSAM (FR) | 1976-01-20 | — | — | US | claimed |
| US-3934008-A | PEPTIDES, HYPOCALCAEMIC | CIBA-GEIGY CORPORATION (US) | 1976-01-20 | — | — | US | claimed |