SCHEMBL14554012

SCHEMBL14554012

CC(=O)[C@H](CCCN)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CCCN)NC(=O)[C@@H](Cc1ccccc1)NC(=O)[C@H](CCCN)NC(=O)[C@@H](CCC(N)=O)NC(=O)[C@@H](N)CCCN

nearest known ligand 0.65

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ GHSR Q92847 9/20 0.65
▸ NPY1R P25929 3/20 0.58
▸ NPY2R P49146 3/20 0.58
▸ NPY4R P50391 3/20 0.58
▸ UTS2R Q9UKP6 1/20 0.55
▸ KISS1R Q969F8 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14553985 0.98 GHSR (0.65) GHSRNPY1RNPY2RNPY4RUTS2R
SCHEMBL17880374 0.98 GHSR (0.65) GHSRNPY1RNPY2RNPY4RUTS2R
SCHEMBL18898969 0.97 GHSR (0.68) GHSRNPY1RNPY2RNPY4RUTS2R
SCHEMBL18256999 0.95 GHSR (0.62) GHSRNPY1RNPY2RNPY4RUTS2R
SCHEMBL17880269 0.94 GHSR (0.63) GHSRNPY1RNPY2RNPY4RUTS2R
SCHEMBL17192784 0.93 GHSR (0.65) GHSRNPY1RNPY2RNPY4RUTS2R
SCHEMBL18899117 0.92 GHSR (0.59) GHSRNPY1RNPY2RNPY4RKISS1R
SCHEMBL17192808 0.91 GHSR (0.65) GHSRNPY1RNPY2RNPY4RUTS2R
SCHEMBL17880376 0.91 GHSR (0.57) GHSRNPY1RNPY2RNPY4RKISS1R
SCHEMBL14553988 0.91 GHSR (0.57) GHSRNPY1RNPY2RNPY4RKISS1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9101687-B2 Beta sheet tapes ribbons in tissue engineering UNIVERSITY OF LEEDS (GB) 2015-08-11 — — US disclosed
US-20130012457-A1 BETA SHEET TAPES RIBBONS IN TISSUE ENGINEERING THE UNIVERSITY OF LEEDS 2013-01-10 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130012457-A1 BETA SHEET TAPES RIBBONS IN TISSUE ENGINEERING IAPP, TAGLN2, KRT18 GHSR 3289/4885NPY1R 3085/4885NPY2R 2895/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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