Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 8/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12515871 | 0.87 | OPRK1 (0.48) | MAPTL3MBTL1POLBKDM4ENPSR1 | |
| SCHEMBL2222580 | 0.87 | OPRK1 (0.52) | MAPTL3MBTL1POLBKDM4ENPSR1 | |
| SCHEMBL2222430 | 0.85 | OPRK1 (0.46) | MAPTL3MBTL1POLBKDM4ENPSR1 | |
| SCHEMBL12517307 | 0.85 | OPRK1 (0.55) | MAPTL3MBTL1POLBKDM4ENPSR1 | |
| SCHEMBL2222432 | 0.83 | MAPT (0.44) | MAPTL3MBTL1POLBKDM4ENPSR1 | |
| SCHEMBL2224091 | 0.82 | OPRK1 (0.55) | MAPTL3MBTL1POLBKDM4ENPSR1 | |
| SCHEMBL2224891 | 0.82 | OPRK1 (0.49) | MAPTL3MBTL1POLBKDM4ENPSR1 | |
| SCHEMBL2222926 | 0.81 | KDM4E (0.55) | MAPTL3MBTL1POLBKDM4ENPSR1 | |
| Hydrochloric Acid SCHEMBL2225694 | 0.80 | KDM4E (0.54) | MAPTL3MBTL1POLBKDM4ENPSR1 | |
| SCHEMBL2222498 | 0.79 | OPRK1 (0.59) | MAPTL3MBTL1POLBKDM4ENPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013006596-A1 | VOLTAGE-GATED SODIUM CHANNEL BLOCKERS | GLAXO GROUP LIMITED (GB) | 2013-01-10 | — | — | WO | disclosed |