Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | CDK4 | P11802 | 2/20 | 0.49 |
| ▸ | CCND1 | P24385 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.49 |
| ▸ | CDK1 | P06493 | 1/20 | 0.49 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.49 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.45 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.44 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.44 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.44 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.44 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.44 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.44 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.44 |
| ▸ | SLC26A4 | O43511 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL498283 | 0.83 | MAOB (0.60) | MAOBKDM4ECDK4CCND1KMT2A | |
| SCHEMBL10452980 | 0.80 | MAOB (0.65) | MAOBKDM4ECDK4CCND1KMT2A | |
| SCHEMBL5606933 | 0.80 | PARP10 (0.55) | MAOBKMT2AFFAR1CHRNB2CHRNB4 | |
| SCHEMBL8264422 | 0.80 | MAOB (0.64) | MAOBKDM4ECDK4CCND1KMT2A | |
| SCHEMBL10865258 | 0.79 | MAOB (0.68) | MAOBKDM4ECDK4CCND1KMT2A | |
| Hydrochloric Acid SCHEMBL23235866 | 0.78 | MAOB (0.62) | MAOBKDM4ECDK4CCND1KMT2A | |
| SCHEMBL11901061 | 0.78 | SIRT2 (0.60) | KMT2AFFAR1 | |
| SCHEMBL1584472 | 0.77 | MAOB (0.61) | MAOBKDM4ECDK4CCND1KMT2A | |
| SCHEMBL21340421 | 0.77 | MAOB (0.61) | MAOBKDM4ECDK4CCND1KMT2A | |
| SCHEMBL11860320 | 0.77 | MAOB (0.61) | MAOBKDM4ECDK4CCND1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013006596-A1 | VOLTAGE-GATED SODIUM CHANNEL BLOCKERS | GLAXO GROUP LIMITED (GB) | 2013-01-10 | — | — | WO | disclosed |