Sugi Predict

Sugi Predict / Compounds / SCHEMBL5606933

SCHEMBL5606933

SCHEMBL5606933

C=Cc1ccc(OCc2ccccc2Br)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PARP10 Q53GL7 1/20 0.55
▸ FFAR1 O14842 1/20 0.51
▸ FFAR4 Q5NUL3 1/20 0.51
▸ MAOB P27338 1/20 0.47
▸ ALDH1A1 P00352 3/20 0.46
▸ IDO1 P14902 2/20 0.46
▸ MAPT P10636 2/20 0.46
▸ HTT P42858 2/20 0.46
▸ NPC1 O15118 1/20 0.46
▸ RAB9A P51151 1/20 0.46
▸ SMN1; SMN2 Q16637 1/20 0.46
▸ CHRNA7 P36544 2/20 0.41
▸ CHRNB2 P17787 1/20 0.41
▸ CHRNB4 P30926 1/20 0.41
▸ CHRNA3 P32297 1/20 0.41
▸ CHRNA4 P43681 1/20 0.41
▸ AR P10275 1/20 0.40
▸ OPRD1 P41143 1/20 0.39
▸ F2 P00734 1/20 0.39
▸ PRSS1 P07477 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15774723 0.83 ALDH1A1 (0.59) PARP10FFAR1FFAR4MAOBALDH1A1
SCHEMBL14554283 0.80 MAOB (0.56) FFAR1FFAR4MAOBCHRNA7CHRNB2
SCHEMBL1259945 0.80 PARP10 (0.62) PARP10FFAR1FFAR4MAOBALDH1A1
SCHEMBL9557449 0.80 PARP10 (0.48) PARP10FFAR1FFAR4MAOBALDH1A1
SCHEMBL11901061 0.78 SIRT2 (0.60) PARP10FFAR1MAPTNPC1RAB9A
SCHEMBL2292141 0.77 PARP10 (0.59) PARP10FFAR1FFAR4MAOBALDH1A1
SCHEMBL2291386 0.77 PARP10 (0.59) PARP10FFAR1FFAR4MAOBALDH1A1
SCHEMBL8846366 0.77 PARP10 (0.59) PARP10FFAR1FFAR4ALDH1A1IDO1
SCHEMBL763259 0.75 LMNA (0.60) MAOBALDH1A1MAPTNPC1RAB9A
SCHEMBL7556795 0.75 RELA (0.49) ALDH1A1MAPTNPC1RAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7169874-B2 High refractive index polymeric siloxysilane compositions BAUSCH & LOMB INCORPORATED (US) 2007-01-30 — — US disclosed
US-7138440-B2 High refractive index polymeric siloxysilane compositions BAUSCH & LOMB INCORPORATED (US) 2006-11-21 — — US disclosed
US-7101949-B2 High refractive index polymeric siloxysilane compositions BAUSCH & LOMB INCORPORATED (US) 2006-09-05 — — US disclosed
US-7091299-B2 High refractive index polymeric siloxysilane compositions BAUSCH & LOMB INCORPORATED (US) 2006-08-15 — — US disclosed
US-6908978-B2 High refractive index polymeric siloxysilane compositions BAUSCH & LOMB INCORPORATED (US) 2005-06-21 — — US disclosed
US-20050131191-A1 High refractive index polymeric siloxysilane compositions SALAMONE JOSEPH C (US) 2005-06-16 — — US disclosed
US-20050131189-A1 High refractive index polymeric siloxysilane compositions SALIX PHARMACEUTICALS, LTD. 2005-06-16 — — US disclosed
US-20050127557-A1 High refractive index polymeric siloxysilane compositions SOLTA MEDICAL, INC. 2005-06-16 — — US disclosed
EP-1465903-A1 HIGH REFRACTIVE INDEX POLYMERIC SILOXYSILANE COMPOSITIONS BAUSCH & LOMB INCORPORATED (US) 2004-10-13 — — EP disclosed
EP-1448572-A1 HIGH REFRACTIVE INDEX POLYMERIC SILOXYSILANE COMPOSITIONS BAUSCH & LOMB INCORPORATED (US) 2004-08-25 — — EP disclosed
US-20030109661-A1 High refractive index polymeric siloxysilane compositions BAUSCH HEALTH US, LLC 2003-06-12 — — US disclosed
US-20030100697-A1 High refractive index polymeric siloxysilane compositions SALIX PHARMACEUTICALS, INC. 2003-05-29 — — US disclosed
WO-2003040158-A1 HIGH REFRACTIVE INDEX POLYMERIC SILOXYSILANE COMPOSITIONS BAUSCH & LOMB INCORPORATED (US) 2003-05-15 — — WO disclosed
WO-2003040157-A1 HIGH REFRACTIVE INDEX POLYMERIC SILOXYSILANE COMPOSITIONS BAUSCH & LOMB INCORPORATED (US) 2003-05-15 — — WO disclosed