Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | MGAM | O43451 | 1/20 | 0.35 |
| ▸ | SI | P14410 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17168358 | 1.00 | LMNA (0.42) | LMNAL3MBTL1TDP1TSHRCYP2C9 | |
| SCHEMBL9246336 | 1.00 | LMNA (0.42) | LMNAL3MBTL1TDP1TSHRCYP2C9 | |
| SCHEMBL11145479 | 1.00 | LMNA (0.42) | LMNAL3MBTL1TDP1TSHRCYP2C9 | |
| SCHEMBL12330492 | 0.94 | LMNA (0.42) | LMNAL3MBTL1TDP1TSHRCYP2C9 | |
| SCHEMBL1780664 | 0.94 | LMNA (0.42) | LMNAL3MBTL1TDP1TSHRCYP2C9 | |
| SCHEMBL18877224 | 0.89 | LMNA (0.35) | LMNAL3MBTL1TDP1TSHRCYP2C9 | |
| SCHEMBL12663200 | 0.88 | TDP1 (0.40) | LMNAL3MBTL1TDP1TSHRMGAM | |
| SCHEMBL6696405 | 0.86 | LMNA (0.50) | LMNAL3MBTL1TDP1MGAMSI | |
| SCHEMBL11146422 | 0.86 | LMNA (0.50) | LMNAL3MBTL1TDP1MGAMSI | |
| SCHEMBL19741472 | 0.86 | LMNA (0.50) | LMNAL3MBTL1TDP1MGAMSI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013004669-A1 | MULTIVALENT OLIGOSACCHARIDES | NATIONAL UNIVERSITY OF IRELAND, GALWAY (IE) | 2013-01-10 | — | — | WO | disclosed |