Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 19/20 | 0.76 |
| ▸ | HDAC6 | Q9UBN7 | 15/20 | 0.76 |
| ▸ | HDAC1 | Q13547 | 7/20 | 0.76 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.60 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.60 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.60 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.60 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.55 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.55 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2227112 | 0.87 | HDAC4 (0.60) | HDAC4HDAC6HDAC1HDAC8HDAC7 | |
| SCHEMBL14645633 | 0.86 | HDAC4 (1.00) | HDAC4HDAC6HDAC1HDAC8HDAC7 | |
| SCHEMBL2225078 | 0.86 | HDAC4 (0.61) | HDAC4HDAC6HDAC1HDAC8HDAC7 | |
| SCHEMBL14485358 | 0.85 | HDAC4 (0.61) | HDAC4HDAC6HDAC1HDAC8HDAC7 | |
| SCHEMBL14485041 | 0.84 | HDAC4 (0.63) | HDAC4HDAC6HDAC1HDAC8HDAC7 | |
| SCHEMBL2283701 | 0.83 | HDAC4 (0.66) | HDAC4HDAC6HDAC1HDAC8HDAC7 | |
| SCHEMBL29757325 | 0.82 | HDAC6 (0.78) | HDAC4HDAC6HDAC1HDAC8HDAC7 | |
| SCHEMBL14554385 | 0.82 | HDAC4 (0.59) | HDAC4HDAC6HDAC1HDAC8HDAC7 | |
| SCHEMBL2362796 | 0.81 | HDAC4 (0.71) | HDAC4HDAC6HDAC1HDAC8HDAC7 | |
| SCHEMBL14554408 | 0.80 | HDAC4 (0.58) | HDAC4HDAC6HDAC1HDAC8HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013006408-A1 | COMPOUNDS AND METHODS | TEMPERO PHARMACEUTICALS, INC. (US) | 2013-01-10 | — | — | WO | disclosed |