Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 18/20 | 0.59 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.58 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.58 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.58 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.58 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.58 |
| ▸ | HDAC6 | Q9UBN7 | 14/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2225078 | 0.83 | HDAC4 (0.61) | HDAC4HDAC1HDAC7HDAC8HDAC9 | |
| SCHEMBL14554362 | 0.82 | HDAC4 (0.76) | HDAC4HDAC1HDAC7HDAC8HDAC9 | |
| SCHEMBL14485358 | 0.81 | HDAC4 (0.61) | HDAC4HDAC1HDAC7HDAC8HDAC9 | |
| SCHEMBL6973570 | 0.80 | HDAC4 (0.59) | HDAC4HDAC1HDAC7HDAC8HDAC9 | |
| SCHEMBL29757325 | 0.80 | HDAC6 (0.78) | HDAC4HDAC1HDAC7HDAC8HDAC9 | |
| SCHEMBL2227112 | 0.80 | HDAC4 (0.60) | HDAC4HDAC1HDAC7HDAC8HDAC9 | |
| SCHEMBL21175486 | 0.79 | HDAC4 (0.61) | HDAC4HDAC1HDAC6 | |
| SCHEMBL14485041 | 0.78 | HDAC4 (0.63) | HDAC4HDAC1HDAC7HDAC8HDAC9 | |
| SCHEMBL2229930 | 0.77 | HDAC4 (0.60) | HDAC4HDAC1HDAC7HDAC8HDAC9 | |
| SCHEMBL2282081 | 0.76 | HDAC4 (0.61) | HDAC4HDAC1HDAC7HDAC8HDAC9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013006408-A1 | COMPOUNDS AND METHODS | TEMPERO PHARMACEUTICALS, INC. (US) | 2013-01-10 | — | — | WO | disclosed |