SCHEMBL14557173

SCHEMBL14557173

c1cc(-c2cc3n(n2)c2cc(-c4ccncc4)nn2c2cc(-c4ccncc4)nn32)ccn1

nearest known ligand 0.44

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.43
MAPT P10636 1/20 0.43
CDC7 O00311 1/20 0.42
FYN P06241 8/20 0.41
KDR P35968 1/20 0.41
DYRK1A Q13627 2/20 0.40
IDO1 P14902 1/20 0.38
KDM5B Q9UGL1 1/20 0.38
NOTUM Q6P988 1/20 0.37
TSHR P16473 1/20 0.37
HTT P42858 1/20 0.37
PIK3CD O00329 1/20 0.37
PIK3CB P42338 1/20 0.37
PIK3CG P48736 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14557157 0.79 NPC1 (0.52) LMNAMAPTHTT
SCHEMBL14557164 0.75 ALDH1A1 (0.46) LMNAMAPTDYRK1A
SCHEMBL23665936 0.71 FYN (0.46) LMNAMAPTFYNHTT
SCHEMBL14560017 0.71 NPC1 (0.44)
SCHEMBL5213490 0.70 MAPK14 (0.43) CDC7FYNKDRPIK3CDPIK3CB
SCHEMBL24378416 0.70 PDE10A (0.50) LMNAMAPTFYNKDRDYRK1A
SCHEMBL2685502 0.68 KDR (0.53) LMNAMAPTCDC7KDRTSHR
SCHEMBL19145066 0.68 DYRK1A (0.41) LMNAMAPTCDC7KDRDYRK1A
SCHEMBL14557180 0.67 CYP1A2 (0.50) LMNAMAPT
SCHEMBL5317887 0.67 CYP11B1 (0.39) LMNAMAPTCDC7FYNKDR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170358767-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT Konica Minolta, Inc. (JP) 2017-12-14 US disclosed
US-20170358767-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT Konica Minolta, Inc. (JP) 2017-12-14 US disclosed
US-20170338446-A1 Organic Electroluminescence Element MERCK PATENT GMBH (DE) 2017-11-23 US disclosed
US-20170338446-A1 Organic Electroluminescence Element MERCK PATENT GMBH (DE) 2017-11-23 US disclosed
US-20170125715-A1 ORGANIC ELECTROLUMINESCENT ELEMENT Konica Minolta, Inc. (JP) 2017-05-04 US disclosed
US-20170125715-A1 ORGANIC ELECTROLUMINESCENT ELEMENT Konica Minolta, Inc. (JP) 2017-05-04 US disclosed
US-20070059554-A1 Organic electroluminescent device FUJI PHOTO FILM CO., LTD. 2007-03-15 US disclosed
US-20070059554-A1 Organic electroluminescent device FUJI PHOTO FILM CO., LTD. 2007-03-15 US disclosed