SCHEMBL14557679

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14557668	0.92	MEN1 (0.41)	PPARGMEN1KMT2AALDH1A1MAPK1
	SCHEMBL14557681	0.92	FFAR4 (0.39)	PPARGMEN1KMT2AMAPK1ROCK2
	SCHEMBL14557669	0.91	PPARG (0.43)	PPARGMEN1KMT2AALDH1A1MAPK1
	SCHEMBL14557677	0.91	MAPK1 (0.41)	PPARGMEN1KMT2AALDH1A1MAPK1
	SCHEMBL14557674	0.90	PPARG (0.45)	PPARGMEN1KMT2AALDH1A1LCLAT1
	SCHEMBL14557713	0.89	PPARG (0.41)	PPARGALDH1A1MAPK1ROCK2RPS6KA5
	SCHEMBL4602734	0.89	ROCK2 (0.40)	PPARGMAPK1ROCK2RPS6KA5RPS6KA4
	SCHEMBL14557678	0.89	PPARG (0.39)	PPARGMEN1KMT2AALDH1A1MAPK1
	SCHEMBL14557672	0.89	PPARG (0.39)	PPARGMEN1KMT2AALDH1A1LCLAT1
	SCHEMBL14557709	0.88	MAPK1 (0.39)	PPARGALDH1A1LCLAT1MAPK1ROCK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.