Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14557892 | 0.87 | ELANE (0.34) | ELANESMN1; SMN2HSD17B10ALDH1A1KMT2A | |
| SCHEMBL14557906 | 0.85 | ELANE (0.33) | ELANESMN1; SMN2NPC1RAB9AHSD17B10 | |
| SCHEMBL14557993 | 0.85 | MAPK1 (0.33) | TSHRLMNAMAPK1HTT | |
| SCHEMBL12807721 | 0.83 | SMN1; SMN2 (0.36) | SMN1; SMN2NPC1USP2RAB9AHSD17B10 | |
| SCHEMBL10066813 | 0.81 | CASP1 (0.36) | SMN1; SMN2NPC1USP2RAB9AHSD17B10 | |
| SCHEMBL12807712 | 0.80 | MEN1 (0.34) | SMN1; SMN2ALDH1A1KMT2AMEN1MAPK1 | |
| SCHEMBL10066823 | 0.79 | CASP1 (0.35) | SMN1; SMN2NPC1RAB9AHSD17B10CYP2C9 | |
| SCHEMBL14364633 | 0.78 | CNR2 (0.32) | CNR2ALDH1A1KMT2ALMNAMAPT | |
| SCHEMBL10067135 | 0.78 | NPC1 (0.30) | SMN1; SMN2NPC1USP2RAB9AHSD17B10 | |
| SCHEMBL13181466 | 0.77 | ELANE (0.37) | ELANESMN1; SMN2NPC1RAB9AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070066759-A1 | Block copolymers and use thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-03-22 | — | — | US | disclosed |