Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HMGCR | P04035 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | PGD | P52209 | 2/20 | 0.38 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.38 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CPT2 | P23786 | 1/20 | 0.32 |
| ▸ | ACLY | P53396 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1941442 | 0.82 | TDP1 (0.43) | TDP1SMN1; SMN2HMGCRCHRM1TBXA2R | |
| SCHEMBL28117913 | 0.82 | TDP1 (0.43) | TDP1SMN1; SMN2HMGCRCHRM1TBXA2R | |
| SCHEMBL1941444 | 0.82 | TDP1 (0.43) | TDP1SMN1; SMN2HMGCRCHRM1TBXA2R | |
| SCHEMBL8853350 | 0.82 | TDP1 (0.43) | TDP1SMN1; SMN2HMGCRCHRM1TBXA2R | |
| SCHEMBL1533821 | 0.81 | TDP1 (0.39) | TDP1SMN1; SMN2HMGCRCHRM1TBXA2R | |
| SCHEMBL321093 | 0.81 | TDP1 (0.39) | TDP1SMN1; SMN2HMGCRCHRM1TBXA2R | |
| SCHEMBL4313364 | 0.81 | TDP1 (0.39) | TDP1SMN1; SMN2HMGCRCHRM1TBXA2R | |
| SCHEMBL28481021 | 0.79 | TDP1 (0.37) | TDP1SMN1; SMN2HMGCRCHRM1TBXA2R | |
| SCHEMBL27873809 | 0.79 | CA2 (0.44) | HMGCRCHRM1TBXA2RADRA1ATSHR | |
| SCHEMBL19788372 | 0.78 | TDP1 (0.40) | TDP1SMN1; SMN2HMGCRCHRM1TBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070071665-A1 | Use of a derivative of aspartic acid as a collector in froth flotation processes | AKZO NOBEL N.V. (NL) | 2007-03-29 | — | — | US | disclosed |