SCHEMBL14558147

SCHEMBL14558147

CC(C)CCCC(C)C1CCC2C3CC=C4CCCC[C@]4(C)C3CC[C@]12C

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
USP2 O75604 2/20 0.74
OSBP P22059 4/20 0.73
RORC P51449 4/20 0.73
CYP46A1 Q9Y6A2 2/20 0.73
OSBP2 Q969R2 2/20 0.73
LMNA P02545 1/20 0.73
ABCB1 P08183 1/20 0.73
POLA1 P09884 1/20 0.66
SRD5A1 P18405 3/20 0.65
CYP19A1 P11511 3/20 0.62
GRIN1 Q05586 2/20 0.62
GRIN2A Q12879 2/20 0.62
NR1H3 Q13133 2/20 0.61
CRYAB P02511 1/20 0.59
HMGCR P04035 1/20 0.59
ITGB3 P05106 1/20 0.59
ITGAV P06756 1/20 0.59
SREBF2 Q12772 1/20 0.59
NPC1L1 Q9UHC9 1/20 0.59
GRIN2B Q13224 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28185721 1.00 USP2 (0.74) USP2OSBPRORCCYP46A1OSBP2
SCHEMBL2631976 1.00 USP2 (0.74) USP2OSBPRORCCYP46A1OSBP2
SCHEMBL932451 1.00 USP2 (0.74) USP2OSBPRORCCYP46A1OSBP2
SCHEMBL14052247 1.00 USP2 (0.74) USP2OSBPRORCCYP46A1OSBP2
SCHEMBL24264118 1.00 USP2 (0.74) USP2OSBPRORCCYP46A1OSBP2
SCHEMBL24927685 1.00 USP2 (0.74) USP2OSBPRORCCYP46A1OSBP2
SCHEMBL11977916 1.00 USP2 (0.74) USP2OSBPRORCCYP46A1OSBP2
SCHEMBL18409785 1.00 USP2 (0.74) USP2OSBPRORCCYP46A1OSBP2
SCHEMBL7601730 1.00 USP2 (0.74) USP2OSBPRORCCYP46A1OSBP2
SCHEMBL17715402 1.00 USP2 (0.74) USP2OSBPRORCCYP46A1OSBP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3147367-A1 SMALL MOLECULE CONJUGATES FOR INTRACELLULAR DELIVERY OF NUCLEIC ACIDS F. Hoffmann-La Roche AG (CH) 2017-03-29 EP disclosed
US-20070054195-A1 Optical recording medium, method of producing the same, and, optical recording method and optical reproducing method FUJI PHOTO FILM CO., LTD. 2007-03-08 US disclosed
US-20070047421-A1 Optical recording method, optical recording apparatus, optical recording medium, and optical reproducing method FUJI PHOTO FILM CO., LTD. 2007-03-01 US disclosed
US-20070047419-A1 Optical recording method, optical recording apparatus, optical recording medium, and optical reproducing method FUJI PHOTO FILM CO., LTD. 2007-03-01 US disclosed
US-20070042275-A1 Composition for optical recording, optical recording medium, and production method thereof FUJI PHOTO FILM CO., LTD. 2007-02-22 US disclosed