Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 2/20 | 0.74 |
| ▸ | OSBP | P22059 | 4/20 | 0.73 |
| ▸ | RORC | P51449 | 4/20 | 0.73 |
| ▸ | CYP46A1 | Q9Y6A2 | 2/20 | 0.73 |
| ▸ | OSBP2 | Q969R2 | 2/20 | 0.73 |
| ▸ | LMNA | P02545 | 1/20 | 0.73 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.73 |
| ▸ | POLA1 | P09884 | 1/20 | 0.66 |
| ▸ | SRD5A1 | P18405 | 3/20 | 0.65 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.62 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.62 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.62 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.61 |
| ▸ | CRYAB | P02511 | 1/20 | 0.59 |
| ▸ | HMGCR | P04035 | 1/20 | 0.59 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.59 |
| ▸ | ITGAV | P06756 | 1/20 | 0.59 |
| ▸ | SREBF2 | Q12772 | 1/20 | 0.59 |
| ▸ | NPC1L1 | Q9UHC9 | 1/20 | 0.59 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28185721 | 1.00 | USP2 (0.74) | USP2OSBPRORCCYP46A1OSBP2 | |
| SCHEMBL2631976 | 1.00 | USP2 (0.74) | USP2OSBPRORCCYP46A1OSBP2 | |
| SCHEMBL932451 | 1.00 | USP2 (0.74) | USP2OSBPRORCCYP46A1OSBP2 | |
| SCHEMBL14052247 | 1.00 | USP2 (0.74) | USP2OSBPRORCCYP46A1OSBP2 | |
| SCHEMBL24264118 | 1.00 | USP2 (0.74) | USP2OSBPRORCCYP46A1OSBP2 | |
| SCHEMBL14558147 | 1.00 | USP2 (0.74) | USP2OSBPRORCCYP46A1OSBP2 | |
| SCHEMBL24927685 | 1.00 | USP2 (0.74) | USP2OSBPRORCCYP46A1OSBP2 | |
| SCHEMBL11977916 | 1.00 | USP2 (0.74) | USP2OSBPRORCCYP46A1OSBP2 | |
| SCHEMBL18409785 | 1.00 | USP2 (0.74) | USP2OSBPRORCCYP46A1OSBP2 | |
| SCHEMBL17715402 | 1.00 | USP2 (0.74) | USP2OSBPRORCCYP46A1OSBP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020166789-A1 | Composition for IVF | NOVO NORDISK A/S (DK) | 2002-11-14 | — | — | US | disclosed |
| US-5929062-A | COMBINATION OF ONE OR MORE OXYSTEROLS AND A SUITABLE CARRIER; ANTICHOLESTEROL AGENTS | UNIVERSITY OF WESTERN ONTARIO (CA) | 1999-07-27 | — | — | US | disclosed |