⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16416569 | 0.86 | PIK3CD (0.41) | — | |
| SCHEMBL7569177 | 0.82 | NAAA (0.48) | — | |
| SCHEMBL11449421 | 0.81 | NAAA (0.44) | — | |
| SCHEMBL11254970 | 0.78 | — | — | |
| SCHEMBL18832718 | 0.78 | — | — | |
| SCHEMBL3145817 | 0.78 | — | — | |
| SCHEMBL1027659 | 0.78 | — | — | |
| SCHEMBL11447863 | 0.75 | NAAA (0.43) | — | |
| SCHEMBL17747689 | 0.74 | NAAA (0.60) | — | |
| SCHEMBL11647947 | 0.73 | CYP2C9 (0.57) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0697408-B1 | 1 substituted-phenyl-oxazolidene-2-one derivatives and their use as adhesion-receptor antagonists | MERCK PATENT GMBH (DE) | 2002-01-23 | — | — | EP | claimed |
| US-5614535-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1997-03-25 | — | — | US | claimed |
| JP-8092227-A | — | — | None | — | — | JP | disclosed |
| WO-2022234852-A1 | PHARMACEUTICAL USE OF CYCLIC PEPTIDE COMPOUND | 中外製薬株式会社 | 2022-11-10 | — | — | WO | disclosed |
| CN-115298176-A | Compounds and their use in the treatment of bacterial infections | 豪夫迈·罗氏有限公司 | 2022-11-04 | — | — | CN | disclosed |
| US-9670237-B2 | Phosphonium-based ionic liquids and their use in the capture of polluting gases | UT-BATTELLE, LLC (US) | 2017-06-06 | — | — | US | disclosed |
| US-20130078170-A1 | PHOSPHONIUM-BASED IONIC LIQUIDS AND THEIR USE IN THE CAPTURE OF POLLUTING GASES | UT BATTELLE (US) | 2013-03-28 | — | — | US | disclosed |
| US-20120258960-A1 | NOVEL MULTIFUNCTIONAL PEPTIDASE INHIBITORS, ESPECIALLY FOR MEDICAL USE | IMTM GMBH (DE) | 2012-10-11 | — | — | US | disclosed |
| WO-2011026781-A1 | NOVEL MULTIFUNCTIONAL PEPTIDASE INHIBITORS, ESPECIALLY FOR MEDICAL USE | IMTM GMBH (DE) | 2011-03-10 | — | — | WO | disclosed |
| EP-2292589-A1 | Novel multifunctional peptidase inhibitors, especially for medical use | IMTM GmbH (DE) | 2011-03-09 | — | — | EP | disclosed |
| CN-101356156-A | Aspartic protease inhibitors | VITAE PHARMACEUTICALS INC (US) | 2009-01-28 | — | — | CN | disclosed |
| CN-1406576-A | Oil in water low emulsifier or non-emulsifier system containing stabilizer and amiho substituted hydroxy diphenyl ketone | BASF AG (DE) | 2003-04-02 | — | — | CN | disclosed |
| CN-1406577-A | Cosmetic W/O emulsion and agents for skin containing amino substituted hydroxy diphenyl ketone | BASF AG (DE) | 2003-04-02 | — | — | CN | disclosed |
| WO-2002045853-A1 | LEWIS ACID CATALYSIS USING CHIRAL METAL COMPLEXES | DOYLE MICHAEL P (US) | 2002-06-13 | — | — | WO | disclosed |
| US-6319932-B1 | USEFUL FOR TREATING BENIGN PROSTATIC HYPERPLASIA | MERCK & CO., INC. | 2001-11-20 | — | — | US | disclosed |
| WO-2000027827-A1 | OXAZOLIDINONES USEFUL AS ALPHA 1A ADRENOCEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 2000-05-18 | — | — | WO | disclosed |
| WO-2000027816-A1 | OXAZOLIDINONES USEFUL AS ALPHA 1A ADRENOCEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 2000-05-18 | — | — | WO | disclosed |
| US-5614535-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1997-03-25 | — | — | US | disclosed |
| JP-H0892227-A | ADHESION RECEPTOR ANTAGONIST | MERCK PATENT GMBH | 1996-04-09 | — | — | JP | disclosed |
| US-5245032-A | CATALYTIC PROCESSES FOR THE PREPARATION OF N,N,N-TRISUBSTITUTED NITROGEN-CONTAINING COMPOUNDS | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1993-09-14 | — | — | US | disclosed |