Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.69 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.69 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Guanidinoethyldisulfide SCHEMBL1321518 | 0.97 | TSHR (0.67) | TSHRHIF1ACYP1A2MEN1KMT2A | |
| SCHEMBL12040362 | 0.91 | TSHR (0.60) | TSHRHIF1ACYP1A2MEN1KMT2A | |
| SCHEMBL13035000 | 0.89 | TSHR (0.58) | TSHRHIF1ACYP1A2MEN1KMT2A | |
| SCHEMBL14215853 | 0.85 | TSHR (0.55) | TSHRHIF1ACYP1A2MEN1KMT2A | |
| SCHEMBL10311296 | 0.84 | TSHR (0.53) | TSHRHIF1ACYP1A2MEN1KMT2A | |
| SCHEMBL7125618 | 0.84 | TSHR (0.53) | TSHRHIF1ACYP1A2MEN1KMT2A | |
| SCHEMBL7063396 | 0.79 | — | — | |
| SCHEMBL3079040 | 0.78 | CYP1A2 (0.48) | TSHRHIF1ACYP1A2MEN1KMT2A | |
| SCHEMBL17029960 | 0.77 | — | — | |
| Hydrochloric Acid SCHEMBL11403921 | 0.76 | MEN1 (0.46) | TSHRHIF1ACYP1A2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 307 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2111135-B1 | ORAL CARE IMPLEMENT HAVING FLUID DELIVERY SYSTEM | COLGATE PALMOLIVE CO (US) | 2018-07-04 | — | — | EP | claimed |
| EP-2117376-B1 | ORAL CARE IMPLEMENT HOUSING AN ORAL CARE AGENT | COLGATE PALMOLIVE CO (US) | 2017-11-15 | — | — | EP | claimed |
| EP-1903905-B1 | ORAL CARE IMPLEMENT HAVING RESERVOIR FOR DISPENSING ACTIVE AGENT | COLGATE PALMOLIVE CO (US) | 2016-12-28 | — | — | EP | claimed |
| US-9398804-B2 | Oral care implement having reservior for dispensing active agent | COLGATE-PALMOLIVE COMPANY (US) | 2016-07-26 | — | — | US | claimed |
| US-9167886-B2 | Oral care implement having fluid delivery system | COLGATE-PALMOLIVE COMPANY (US) | 2015-10-27 | — | — | US | claimed |
| US-8920168-B2 | Oral care implement having fluid delivery system | COLGATE-PALMOLIVE COMPANY (US) | 2014-12-30 | — | — | US | claimed |
| EP-2328510-B1 | ORAL CARE IMPLEMENT WITH CAVITATION SYSTEM | COLGATE PALMOLIVE CO (US) | 2014-10-15 | — | — | EP | claimed |
| US-20140068882-A1 | Oral Care Implement Having Fluid Delivery System | COLGATE-PALMOLIVE COMPANY (US) | 2014-03-13 | — | — | US | claimed |
| US-20130305471-A1 | Oral Care Implement Having Fluid Delivery System | COLGATE-PALMOLIVE COMPANY (US) | 2013-11-21 | — | — | US | claimed |
| US-8517728-B2 | Oral care implement having fluid delivery system | COLGATE-PALMOLIVE COMPANY (US) | 2013-08-27 | — | — | US | claimed |
| US-20090169608-A1 | TOPICALLY APPLICABLE COMPOSITION FOR USE AS A SKIN BLEACHING AGENT | DSM IP ASSETS B.V. (NL) | 2009-07-02 | — | — | US | claimed |
| US-20080181716-A1 | Oral Care Implement Housing an Oral Care Agent | COLGATE-PALMOLIVE COMPANY | 2008-07-31 | — | — | US | claimed |
| WO-2008091933-A1 | ORAL CARE IMPLEMENT HOUSING AN ORAL CARE AGENT | COLGATE-PALMOLIVE COMPANY (US) | 2008-07-31 | — | — | WO | claimed |
| WO-2008091935-A2 | ORAL CARE IMPLEMENT HAVING FLUID DELIVERY SYSTEM | COLGATE-PALMOLIVE COMPANY (US) | 2008-07-31 | — | — | WO | claimed |
| US-20080176183-A1 | Oral Care Implement Having Fluid Delivery System | INNOVATIVE WATER CARE, LLC | 2008-07-24 | — | — | US | claimed |
| EP-1945308-A1 | TOPICALLY APPLICABLE COMPOSITION FOR USE AS A SKIN BLEACHING AGENT | DSMIP Assets B.V. (NL) | 2008-07-23 | — | — | EP | claimed |
| EP-1903905-A1 | ORAL CARE IMPLEMENT HAVING RESERVOIR FOR DISPENSING ACTIVE AGENT | Colgate-Palmolive Company (US) | 2008-04-02 | — | — | EP | claimed |
| US-20070154863-A1 | Oral Care Implement Having Reservior for Dispensing Active Agent | COLGATE-PALMOLIVE COMPANY (US) | 2007-07-05 | — | — | US | claimed |
| WO-2007041884-A1 | TOPICALLY APPLICABLE COMPOSITION FOR USE AS A SKIN BLEACHING AGENT | DSM IP ASSETS B.V. (NL) | 2007-04-19 | — | — | WO | claimed |
| WO-2007008908-A1 | ORAL CARE IMPLEMENT HAVING RESERVOIR FOR DISPENSING ACTIVE AGENT | COLGATE-PALMOLIVE COMPANY (US) | 2007-01-18 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090169608-A1 | TOPICALLY APPLICABLE COMPOSITION FOR USE AS A SKIN BLEACHING AGENT | SPTBN1, SPTAN1, TYR | TSHR 4095/4885HIF1A 2232/4885CYP1A2 1307/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.