Sugi Predict

Sugi Predict / Targets / SPTAN1

SPTAN1

Spectrin alpha chain, non-erythrocytic 1 · Q13813 · SPTAN1 on Sugi Atlas →

0 patent compounds predicted against SPTAN1, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to SPTAN1 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Hereditary Sensory Neuropathy Serine Trial PHASE2UNKNOWN
Efficacy and Safety Assessment of Oral LBH589 in Adult Patients With Advanced Soft TIssue Sarcoma After Pre-treatment Failure PHASE2COMPLETED
Phase 1/ Phase 2 Study to Assess Safety and Efficacy of Orally Administered JBI-802 in Subjects With Myeloproliferative Neoplasms (MPN) and Myelodysplastic/Myeloproliferative Neoplasms (MDS/MPN) With Thrombocytosis PHASE1/PHASE2RECRUITING
Hemolysis in Patients With Hereditary Spherocytosis (HS) nanUNKNOWN
A Novel Mutation of the Spectrin Gene nanCOMPLETED
Hereditary Spastic Paraplegia Genomic Sequencing Initiative (HSPseq) nanRECRUITING
Congenital Hemolytic and Dyserythropoietic Anemias nanRECRUITING
Study of Constitutional Platelet Disease nanUNKNOWN
Biomarkers and Validation of Selected Outcome Measures (CMTBiomarker) nanCOMPLETED
Identifying Genes and Mutations Underlying Retinitis Pigmentosa and Allied Diseases nanUNKNOWN
Molecular Genetic Epidemiology of Endocardial Cushion Defects - SCOR in Pediatric Cardiovascular Disease nanCOMPLETED
Scottish Advanced Fetal Research Study nanRECRUITING
MEHMO Natural History and Biomarkers nanRECRUITING
Maternal Genes and Epimutations: Beckwith-Wiedemann Syndrome & Reproductive Risks nanRECRUITING
Evaluation of Brain Dysfunction in Patients with Duchene Muscular Dystrophy nanNOT_YET_RECRUITING
Development of Non-Invasive Prenatal Diagnosis for Single Gene Disorders nanRECRUITING
CP-EDIT: Cerebral Palsy - Early Diagnosis and Intervention Trial nanRECRUITING
Investigations Into ISCU Myopathy or Iron Sulfur Scaffold U Protein Myopathy nanCOMPLETED
Relationship of Gestational Age and Urine Concentration of S100B in Preterm and Term Infants in the First Week of Life nanCOMPLETED
Screening for Alpha Thalassemia in Healthy Volunteers nanACTIVE_NOT_RECRUITING
Longitudinal Study of Neurogenetic Disorders nanRECRUITING
Delineating the Molecular Spectrum and the Clinical, Imaging and Neuronal Phenotype of Chopra-Amiel-Gordon Syndrome nanRECRUITING
Hemochromatosis and Iron Overload Screening Study (HEIRS) nanCOMPLETED
Pulmonary Hypertension--Mechanisms and Family Registry nanCOMPLETED
The Myelin Disorders Biorepository Project nanRECRUITING
Role of SF3B1 Mutation in Assessment of Acute and Chronic Lymphatic Leukemia nanNOT_YET_RECRUITING
Whole Genome Scan of Extended Families With Familial Vocal Cord Paralysis nanCOMPLETED
Genetic Aspects of Neurologic and Psychiatric Disorders nanCOMPLETED
Investigation of Polymorphisms in Bronchopulmonary Dysplasia In Turkish Population nanCOMPLETED
Genetic Factors Affecting the Severity of Beta Thalassemia nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a SPTAN1 binder may also engage these)

ProteinNameSimilarity
P07751 — 1.000 P07751 →
P16546 — 1.000 P16546 →
P16086 — 1.000 P16086 →
P13395 — 0.992 P13395 →
Q62261 — 0.983 Q62261 →
SPTBN1 Spectrin beta chain, non-erythrocytic 1 0.981 landscape →
P02549 — 0.976 P02549 →
Q00963 — 0.973 Q00963 →
P08032 — 0.973 P08032 →
O15020 — 0.972 O15020 →
P15508 — 0.972 P15508 →
P11277 — 0.971 P11277 →
Q9QWN8 — 0.970 Q9QWN8 →
Q08043 — 0.963 Q08043 →
O88990 — 0.962 O88990 →
Q90734 — 0.959 Q90734 →
Q9JI91 — 0.959 Q9JI91 →
P18091 — 0.958 P18091 →
Q3ZC55 — 0.958 Q3ZC55 →
P35609 — 0.958 P35609 →
P57780 — 0.957 P57780 →
Q7PKQ5 — 0.957 Q7PKQ5 →
Q5RCS6 — 0.957 Q5RCS6 →
A5D7D1 — 0.957 A5D7D1 →
Q0III9 — 0.957 Q0III9 →
Q3B7N2 — 0.956 Q3B7N2 →
L7UZ85 — 0.956 L7UZ85 →
ACTN4 Alpha-actinin-4 0.956 landscape →
Q2PFV7 — 0.956 Q2PFV7 →
Q9H254 — 0.955 Q9H254 →