Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HINT1 | P49773 | 4/20 | 0.67 |
| ▸ | NT5E | P21589 | 1/20 | 0.67 |
| ▸ | HPGD | P15428 | 1/20 | 0.65 |
| ▸ | GSK3A | P49840 | 2/20 | 0.62 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.62 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.62 |
| ▸ | TGM2 | P21980 | 1/20 | 0.61 |
| ▸ | KRAS | P01116 | 9/20 | 0.60 |
| ▸ | PNP | P00491 | 1/20 | 0.60 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5354648 | 1.00 | HINT1 (0.67) | HINT1NT5EHPGDGSK3ARPS6KA3 | |
| SCHEMBL5354652 | 1.00 | HINT1 (0.67) | HINT1NT5EHPGDGSK3ARPS6KA3 | |
| SCHEMBL16114035 | 0.90 | HINT1 (0.68) | HINT1NT5EHPGDGSK3ARPS6KA3 | |
| Guanosine SCHEMBL7062800 | 0.90 | HPGD (0.76) | HINT1NT5EHPGDGSK3ARPS6KA3 | |
| Guanosine SCHEMBL10811044 | 0.90 | HPGD (0.76) | HINT1NT5EHPGDGSK3ARPS6KA3 | |
| Guanosine SCHEMBL24049416 | 0.90 | HPGD (0.76) | HINT1NT5EHPGDGSK3ARPS6KA3 | |
| Guanosine SCHEMBL24049467 | 0.90 | HPGD (0.76) | HINT1NT5EHPGDGSK3ARPS6KA3 | |
| Guanosine SCHEMBL24049417 | 0.90 | HPGD (0.76) | HINT1NT5EHPGDGSK3ARPS6KA3 | |
| Guanosine SCHEMBL20750695 | 0.90 | HPGD (0.76) | HINT1NT5EHPGDGSK3ARPS6KA3 | |
| Guanosine SCHEMBL24049608 | 0.90 | HPGD (0.76) | HINT1NT5EHPGDGSK3ARPS6KA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7189706-B2 | C2,5′-disubstituted and N6,C2,5′-trisubstituted adenosine derivatives and pharmaceutical compositions containing them | UNIVERSITEIT LEIDEN (NL) | 2007-03-13 | — | — | US | disclosed |