Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 18/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5360822 | 0.96 | MAOA (0.63) | MAOACYP3A4CYP2D6CYP2C9 | |
| SCHEMBL6071683 | 0.94 | MAOA (0.61) | MAOACYP3A4CYP2D6CYP2C9 | |
| SCHEMBL14559473 | 0.93 | MAOA (0.62) | MAOACYP3A4CYP2D6CYP2C9 | |
| SCHEMBL14559470 | 0.93 | MAOA (0.65) | MAOACYP3A4CYP2D6CYP2C9 | |
| Hydrochloric Acid SCHEMBL5409361 | 0.92 | MAOA (0.60) | MAOACYP3A4CYP2D6CYP2C9 | |
| SCHEMBL14559490 | 0.92 | MAOA (0.60) | MAOACYP3A4CYP2D6CYP2C9 | |
| SCHEMBL14559469 | 0.91 | MAOA (0.63) | MAOACYP3A4CYP2D6CYP2C9 | |
| SCHEMBL6274960 | 0.91 | MAOA (0.56) | MAOACYP3A4CYP2D6CYP2C9 | |
| SCHEMBL5407026 | 0.91 | MAOA (0.62) | MAOACYP3A4CYP2D6CYP2C9 | |
| SCHEMBL6070815 | 0.90 | MAOA (0.70) | MAOACYP3A4CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7192974-B2 | Hydroxymethyl substituted dihydroisoxazole derivatives useful as antibiotic agents | ASTRAZENECA AB (SE) | 2007-03-20 | — | — | US | disclosed |
| US-7192974-B2 | Hydroxymethyl substituted dihydroisoxazole derivatives useful as antibiotic agents | ASTRAZENECA AB (SE) | 2007-03-20 | — | — | US | disclosed |