Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 17/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4758912 | 1.00 | MAOA (0.62) | MAOACYP3A4CYP2D6CYP2C9 | |
| SCHEMBL14559464 | 0.95 | MAOA (0.61) | MAOACYP3A4CYP2D6CYP2C9 | |
| SCHEMBL4758755 | 0.92 | MAOA (0.60) | MAOACYP3A4CYP2D6CYP2C9 | |
| SCHEMBL4758751 | 0.92 | MAOA (0.60) | MAOACYP3A4CYP2D6CYP2C9 | |
| SCHEMBL6071030 | 0.92 | MAOA (0.60) | MAOACYP3A4CYP2D6CYP2C9 | |
| SCHEMBL14559468 | 0.92 | MAOA (0.65) | MAOACYP3A4CYP2D6CYP2C9 | |
| SCHEMBL14559474 | 0.92 | MAOA (0.68) | MAOACYP3A4CYP2D6CYP2C9 | |
| SCHEMBL5365406 | 0.92 | MAOA (0.58) | MAOACYP3A4CYP2D6CYP2C9 | |
| Hydrochloric Acid SCHEMBL4701430 | 0.92 | MAOA (0.62) | MAOACYP3A4CYP2D6CYP2C9 | |
| SCHEMBL4702593 | 0.92 | MAOA (0.62) | MAOACYP3A4CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7192974-B2 | Hydroxymethyl substituted dihydroisoxazole derivatives useful as antibiotic agents | ASTRAZENECA AB (SE) | 2007-03-20 | — | — | US | disclosed |
| US-7192974-B2 | Hydroxymethyl substituted dihydroisoxazole derivatives useful as antibiotic agents | ASTRAZENECA AB (SE) | 2007-03-20 | — | — | US | disclosed |