Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 5/20 | 0.36 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.35 |
| ▸ | NAAA | Q02083 | 1/20 | 0.35 |
| ▸ | IDH1 | O75874 | 2/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.33 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3126602 | 1.00 | PTPN1 (0.37) | PTPN1GRM2ACE2NAAAIDH1 | |
| SCHEMBL3123772 | 1.00 | PTPN1 (0.37) | PTPN1GRM2ACE2NAAAIDH1 | |
| SCHEMBL3123763 | 1.00 | PTPN1 (0.37) | PTPN1GRM2ACE2NAAAIDH1 | |
| SCHEMBL1199189 | 0.97 | NAAA (0.35) | PTPN1GRM2NAAAIDH1PTGDR2 | |
| SCHEMBL1199188 | 0.97 | NAAA (0.35) | PTPN1GRM2NAAAIDH1PTGDR2 | |
| SCHEMBL7154474 | 0.92 | IDH1 (0.35) | NAAAIDH1PTGDR2 | |
| SCHEMBL1198446 | 0.92 | IDH1 (0.35) | NAAAIDH1PTGDR2 | |
| SCHEMBL3744875 | 0.92 | IDH1 (0.35) | NAAAIDH1PTGDR2 | |
| SCHEMBL1198445 | 0.92 | IDH1 (0.35) | NAAAIDH1PTGDR2 | |
| SCHEMBL3112094 | 0.92 | IDH1 (0.35) | NAAAIDH1PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7189747-B2 | Method of treating noninflammatory cartilage damage | WARNER-LAMBERT COMPANY (US) | 2007-03-13 | — | — | US | disclosed |