Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NOS1 | P29475 | 2/20 | 0.39 |
| ▸ | NOS3 | P29474 | 1/20 | 0.39 |
| ▸ | CDA | P32320 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14571049 | 1.00 | GAA (0.50) | GAAMEN1KMT2AMAPTKDM4E | |
| SCHEMBL14290050 | 1.00 | GAA (0.50) | GAAMEN1KMT2AMAPTKDM4E | |
| SCHEMBL2878135 | 1.00 | — | — | |
| SCHEMBL460241 | 1.00 | — | — | |
| SCHEMBL24603324 | 0.93 | MEN1 (0.44) | GAAMEN1KMT2AMAPTKDM4E | |
| SCHEMBL2521564 | 0.93 | MEN1 (0.44) | GAAMEN1KMT2AMAPTKDM4E | |
| SCHEMBL12939957 | 0.81 | KMT2A (0.46) | GAAMEN1KMT2AMAPTKDM4E | |
| SCHEMBL23200863 | 0.81 | KMT2A (0.46) | GAAMEN1KMT2AMAPTKDM4E | |
| SCHEMBL6531351 | 0.80 | NOS1 (0.42) | GAAMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL24446066 | 0.78 | MEN1 (0.44) | GAAMEN1KMT2AMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7186828-B2 | Cyclic urea compounds and preparation thereof | IMMUPHARMA (FRANCE) SA (FR) | 2007-03-06 | — | — | US | disclosed |