Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 8/20 | 0.56 |
| ▸ | PPARG | P37231 | 7/20 | 0.56 |
| ▸ | PPARD | Q03181 | 6/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | ACACB | O00763 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | PDE4A | P27815 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | PTGES | O14684 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5380492 | 0.92 | PPARA (0.54) | PPARAPPARGPPARDSMN1; SMN2MEN1 | |
| SCHEMBL6574076 | 0.91 | PPARA (0.53) | PPARAPPARGPPARDMEN1KMT2A | |
| SCHEMBL5353565 | 0.91 | PPARA (0.53) | PPARAPPARGPPARDMEN1KMT2A | |
| SCHEMBL5374825 | 0.91 | PPARA (0.56) | PPARAPPARGPPARDMEN1KMT2A | |
| SCHEMBL5578945 | 0.91 | PPARA (0.56) | PPARAPPARGPPARDMEN1KMT2A | |
| SCHEMBL5382224 | 0.91 | PPARA (0.53) | PPARAPPARGPPARDMEN1KMT2A | |
| SCHEMBL5390548 | 0.91 | PPARA (0.53) | PPARAPPARGPPARDMEN1KMT2A | |
| SCHEMBL14392322 | 0.90 | PPARG (0.58) | PPARAPPARGPPARDSMN1; SMN2MAPK1 | |
| SCHEMBL6572930 | 0.89 | PPARA (0.55) | PPARAPPARGPPARDMEN1KMT2A | |
| SCHEMBL5379964 | 0.89 | PPARA (0.53) | PPARAPPARGPPARDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7192982-B2 | Modulators of peroxisome proliferator activated receptors | LIGAND PHARMACEUTICALS, INC. (US) | 2007-03-20 | — | — | US | disclosed |