Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 14/20 | 0.55 |
| ▸ | PPARG | P37231 | 11/20 | 0.55 |
| ▸ | PPARD | Q03181 | 9/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | PTGES | O14684 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5380135 | 1.00 | PPARA (0.55) | PPARAPPARGPPARDMEN1KMT2A | |
| SCHEMBL14560652 | 0.89 | PPARA (0.56) | PPARAPPARGPPARDMEN1KMT2A | |
| SCHEMBL5381299 | 0.89 | APEX1 (0.40) | PPARAPPARGPPARD | |
| SCHEMBL5578945 | 0.88 | PPARA (0.56) | PPARAPPARGPPARDMEN1KMT2A | |
| SCHEMBL5374825 | 0.88 | PPARA (0.56) | PPARAPPARGPPARDMEN1KMT2A | |
| SCHEMBL5380492 | 0.87 | PPARA (0.54) | PPARAPPARGPPARDMEN1KMT2A | |
| SCHEMBL5391732 | 0.86 | PPARA (0.54) | PPARAPPARGPPARDMEN1KMT2A | |
| SCHEMBL14560622 | 0.86 | PPARA (0.64) | PPARAPPARGPPARDMEN1KMT2A | |
| SCHEMBL5353565 | 0.86 | PPARA (0.53) | PPARAPPARGPPARDMEN1KMT2A | |
| SCHEMBL5382224 | 0.86 | PPARA (0.53) | PPARAPPARGPPARDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1392637-A2 | MODULATORS OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS | ELI LILLY AND COMPANY (US) | 2004-03-03 | — | — | EP | disclosed |
| WO-2002100813-A2 | MODULATORS OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS | ELI LILLY AND COMPANY (US) | 2002-12-19 | — | — | WO | disclosed |