Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 14/20 | 0.68 |
| ▸ | PPARG | P37231 | 11/20 | 0.68 |
| ▸ | PPARD | Q03181 | 10/20 | 0.68 |
| ▸ | ACACB | O00763 | 5/20 | 0.54 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5375792 | 0.92 | PPARA (0.80) | PPARAPPARGPPARDACACBFFAR1 | |
| SCHEMBL5375797 | 0.92 | PPARA (0.80) | PPARAPPARGPPARDACACBFFAR1 | |
| SCHEMBL14560737 | 0.91 | PPARA (0.59) | PPARAPPARGPPARDACACB | |
| SCHEMBL14560768 | 0.88 | PPARA (0.86) | PPARAPPARGPPARDACACBFFAR1 | |
| SCHEMBL14560864 | 0.84 | PPARG (0.76) | PPARAPPARGPPARDACACB | |
| SCHEMBL14560831 | 0.83 | PPARG (0.83) | PPARAPPARGPPARDACACB | |
| SCHEMBL14560732 | 0.83 | PPARG (0.83) | PPARAPPARGPPARDACACB | |
| SCHEMBL6574322 | 0.83 | PPARA (0.70) | PPARAPPARGPPARDACACB | |
| SCHEMBL5392011 | 0.83 | PPARG (0.70) | PPARAPPARGPPARD | |
| SCHEMBL5385194 | 0.83 | PPARA (0.66) | PPARAPPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7192982-B2 | Modulators of peroxisome proliferator activated receptors | LIGAND PHARMACEUTICALS, INC. (US) | 2007-03-20 | — | — | US | disclosed |