Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 17/20 | 0.70 |
| ▸ | PPARG | P37231 | 16/20 | 0.70 |
| ▸ | PPARD | Q03181 | 8/20 | 0.70 |
| ▸ | SRR | Q9GZT4 | 2/20 | 0.47 |
| ▸ | ACACB | O00763 | 1/20 | 0.46 |
| ▸ | PSAT1 | Q9Y617 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5375792 | 0.91 | PPARA (0.80) | PPARAPPARGPPARDACACB | |
| SCHEMBL5375797 | 0.91 | PPARA (0.80) | PPARAPPARGPPARDACACB | |
| SCHEMBL6574440 | 0.91 | PPARG (0.70) | PPARAPPARGPPARDSRRPSAT1 | |
| SCHEMBL6572462 | 0.89 | PPARA (0.56) | PPARAPPARGPPARDACACB | |
| SCHEMBL6571555 | 0.89 | PPARA (0.71) | PPARAPPARGPPARDSRRPSAT1 | |
| SCHEMBL6575247 | 0.88 | PPARA (0.55) | PPARAPPARGPPARD | |
| SCHEMBL6572125 | 0.85 | PPARA (0.58) | PPARAPPARGPPARD | |
| SCHEMBL6575428 | 0.85 | PPARA (0.58) | PPARAPPARGPPARD | |
| SCHEMBL5382474 | 0.84 | PPARG (0.92) | PPARAPPARGPPARD | |
| SCHEMBL5382488 | 0.84 | PPARG (0.92) | PPARAPPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1392637-A2 | MODULATORS OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS | ELI LILLY AND COMPANY (US) | 2004-03-03 | — | — | EP | claimed |
| WO-2002100813-A2 | MODULATORS OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS | ELI LILLY AND COMPANY (US) | 2002-12-19 | — | — | WO | claimed |