Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 15/20 | 0.67 |
| ▸ | PPARD | Q03181 | 12/20 | 0.67 |
| ▸ | PPARG | P37231 | 12/20 | 0.67 |
| ▸ | ACACB | O00763 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14560794 | 0.90 | PPARA (0.68) | PPARAPPARDPPARGACACBESR1 | |
| SCHEMBL5386010 | 0.90 | PPARG (0.83) | PPARAPPARDPPARG | |
| SCHEMBL5389900 | 0.90 | PPARG (0.83) | PPARAPPARDPPARG | |
| SCHEMBL14560735 | 0.90 | PPARG (0.83) | PPARAPPARDPPARG | |
| SCHEMBL14560824 | 0.87 | PPARD (0.67) | PPARAPPARDPPARG | |
| SCHEMBL14560862 | 0.85 | PPARG (0.76) | PPARAPPARDPPARG | |
| SCHEMBL6504323 | 0.85 | PPARA (0.76) | PPARAPPARDPPARG | |
| SCHEMBL16743963 | 0.84 | ESR1 (0.56) | PPARAPPARDPPARGESR1ESR2 | |
| SCHEMBL14560849 | 0.83 | PPARG (0.57) | PPARAPPARDPPARGACACB | |
| SCHEMBL5578945 | 0.82 | PPARA (0.56) | PPARAPPARDPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7192982-B2 | Modulators of peroxisome proliferator activated receptors | LIGAND PHARMACEUTICALS, INC. (US) | 2007-03-20 | — | — | US | disclosed |