Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 4/20 | 0.56 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.56 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | MIF | P14174 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 2/20 | 0.42 |
| ▸ | PPARD | Q03181 | 2/20 | 0.42 |
| ▸ | PPARA | Q07869 | 2/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | F13A1 | P00488 | 1/20 | 0.41 |
| ▸ | LDHA | P00338 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4941128 | 0.85 | PPARA (0.56) | ESR1ESR2SLC7A5PPARGPPARD | |
| SCHEMBL4451311 | 0.85 | PPARA (0.56) | ESR1ESR2SLC7A5PPARGPPARD | |
| SCHEMBL3466702 | 0.85 | PPARA (0.56) | ESR1ESR2SLC7A5PPARGPPARD | |
| SCHEMBL14560811 | 0.84 | PPARA (0.67) | ESR1ESR2PPARGPPARDPPARA | |
| SCHEMBL5606989 | 0.84 | PPARA (0.55) | ESR1ESR2SLC7A5PPARGPPARD | |
| SCHEMBL5607756 | 0.84 | PPARA (0.55) | ESR1ESR2SLC7A5PPARGPPARD | |
| SCHEMBL5607096 | 0.84 | PPARA (0.55) | ESR1ESR2SLC7A5PPARGPPARD | |
| SCHEMBL5606722 | 0.84 | PPARA (0.55) | ESR1ESR2SLC7A5PPARGPPARD | |
| SCHEMBL4811729 | 0.84 | PPARA (0.55) | ESR1ESR2SLC7A5PPARGPPARD | |
| Ammonia Solution, Strong SCHEMBL5606748 | 0.84 | PPARA (0.55) | ESR1ESR2SLC7A5PPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9040531-B2 | Alpha helix mimetics and methods relating thereto | Prism BioLab Co., Ltd. (JP) | 2015-05-26 | — | — | US | disclosed |