Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14563092 | 1.00 | CTSK (0.59) | CTSKCTSB | |
| SCHEMBL14563240 | 0.95 | CTSK (0.57) | CTSKCTSB | |
| SCHEMBL14563005 | 0.91 | CTSK (0.61) | CTSKCTSB | |
| SCHEMBL14563131 | 0.90 | CTSK (0.60) | CTSKCTSB | |
| SCHEMBL14563095 | 0.90 | CTSK (0.63) | CTSKCTSB | |
| SCHEMBL14563098 | 0.90 | CTSK (0.62) | CTSKCTSB | |
| SCHEMBL14642112 | 0.89 | CTSK (0.74) | CTSKCTSB | |
| SCHEMBL2243047 | 0.89 | CTSK (0.74) | CTSKCTSB | |
| SCHEMBL2243793 | 0.89 | CTSK (0.74) | CTSKCTSB | |
| SCHEMBL14563110 | 0.89 | CTSK (0.61) | CTSKCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2170879-B1 | 1-CYANOCYCLOPROPYL-DERIVATIVES AS CATHEPSIN K INHIBITORS | ASTRAZENECA AB (SE) | 2013-01-16 | — | — | EP | claimed |